Results 41 to 50 of about 2,655,730 (261)

The effects of temperature on nitrous oxide and oxygen mixture homogeneity and stability

BMC Anesthesiology, 2010
Background For many long standing practices, the rationale for them is often lost as time passes. This is the situation with respect to the storage and handling of equimolar 50% nitrous oxide and 50% oxygen volume/volume (v/v) mixtures.
Litwin Patrick D
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Development and evaluation of automated ultrasonographic detection of bladder diameter for estimation of bladder urine volume.

PLoS ONE, 2019
Bladder urine volume has been estimated using an ellipsoid method based on triaxial measurements of the bladder extrapolated from two-dimensional ultrasound images.
Masaru Matsumoto, Takuya Tsutaoka, Koichi Yabunaka, Mayumi Handa, Mikako Yoshida, Gojiro Nakagami, Hiromi Sanada   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Avant-propos au volume La notion de « chaîne opératoire » dans le monde : 50 ans d'études technologiques en Préhistoire

Journal of Lithic Studies, 2017
En 1964 s'est tenu aux Eyzies un symposium franco-américain auquel participèrent notamment Fr. Bordes, D. E. Crabtree et J. Tixier, décrit ensuite comme « une pierre de fondation de l’approche technologique » par C. Perlès en 1991.
Yan Axel Gómez Coutouly
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

PENGARUH VARIASI ORIENTASI dan FRAKSI VOLUME SERAT ECENG GONDOK TERHADAP KEKUATAN UJI IMPACT KOMPOSIT SERAT ECENG GONDOK

Ring Mechanical Engineering
Komposit adalah sekumpulan material yang terbuat dari 2 bahan atau lebih dan diperkuat dengan perlakuan tertentu. Untuk memperkuat komposit dapat dilakukan melalui perlakuan Alkalisasi artinya serat direndam dalam larutan Naoh selama waktu yang ...
Izza Rosidi, Mochammad Basjir, Artono Raharjo   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Ultrahigh-pressure generation above 50 GPa in a Kawai-type large-volume press

Matter and Radiation at Extremes
The ability to generate high pressures in a large-volume press (LVP) is crucial for the study of matter under extreme conditions. Here, we have achieved ultrahigh pressures of ∼60 and 50 GPa, respectively, at room temperature and a high temperature of ...
Xinyu Zhao, Fenglin Ren, Jinze He, Yue Pan, Hu Tang, Xiaoming Zhang, Di Yao, Ran Liu, Kuo Hu, Zhaodong Liu, Bingbing Liu   +10 more
doaj   +1 more source