Results 81 to 90 of about 11,600,138 (309)

Robotic prostatectomy for large-volume prostates in prostate cancer: a retrospective analysis of 50 cases (>100 ml)

open access: yesBMC Cancer
Objective To assess the clinical application and efficacy of robotic radical prostatectomy in 50 cases of large-volume (> 100 ml) prostate cancer. Method A retrospective analysis was conducted on 50 patients with large-volume (> 100 ml) prostate cancer ...
Ye Wang   +7 more
doaj   +1 more source

Echocardiographic assessment of left atrial structure and function in severe aortic stenosis with preserved vs. reduced left ventricular ejection fraction

open access: yesFrontiers in Cardiovascular Medicine
IntroductionThis study investigated the changes in left atrial (LA) structure and function in patients with severe aortic stenosis (AS) by comparing those with preserved left ventricular ejection fraction (LVEF) to those with reduced LVEF.MethodsPatients
Yao Zhang   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Volume 50 Index

open access: yesDemography, 2013
Alicia G. VanOrman   +1 more
semanticscholar   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Index of Volume 50

open access: yesHorticultural Science, 2023
Editorial Office
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Contributors to Volume 50, Number 4

open access: yesNames, 2002
Names: A Journal of Onomastics
doaj   +1 more source

Evidence for decreasing quality of semen during past 50 years.

open access: yesBritish medical journal, 1992
E. Carlsen   +3 more
semanticscholar   +1 more source

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