Yosuke Yamada,1,2 Yoshihisa Masuo,3 Eitaro Nakamura,4 Shingo Oda5 1Laboratory of Sports and Health Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2Japan Society for the Promotion of Science, Tokyo, Japan; 3Waseda University Research ...
Yamada Y, Masuo Y, Nakamura E, Oda S
doaj
Volume capture and volume reflection of ultrarelativistic particles in bent single crystals [PDF]
Influence of volume capture on a process of volume reflection of ultrarelativistic particles moving in bent single crystals was considered analytically. Relations describing various distributions of particles involving in the process, the probability of volume capture and behavior of channeling and dechanneling fractions of a beam were obtained ...
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Volume of Distribution is Unaffected by Metabolic Drug-Drug Interactions. [PDF]
Sodhi JK, Huang CH, Benet LZ.
europepmc +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
Impact of the Volume and Distribution of Training Datasets in the Development of Deep-Learning Models for the Diagnosis of Colorectal Polyps in Endoscopy Images. [PDF]
Gong EJ+4 more
europepmc +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Models Used to Predict Chemical Bioaccumulation in Fish from in Vitro Biotransformation Rates Require Accurate Estimates of Blood-Water Partitioning and Chemical Volume of Distribution. [PDF]
Saunders LJ, Nichols JW.
europepmc +1 more source
Improved mathematical models of statistical regularities in precipitation [PDF]
The paper presents improved mathematical models and methods for statistical regularities in the behavior of some important characteristics of precipitation: duration of a wet period, maximum daily and total precipitation volumes within a such period. The asymptotic approximations are deduced using limit theorems for statistics constructed from samples ...
arxiv
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source