Results 11 to 20 of about 5,814,761 (295)
QSAR Models for Predicting Oral Bioavailability and Volume of Distribution and Their Application in Mapping the TK Space of Endocrine Disruptors [PDF]
Journal of XenobioticsToxicokinetic (TK) properties are essential in the framework of chemical risk assessment and drug discovery. Specifically, a TK profile provides information about the fate of chemicals in the human body.
Guillaume Ollitrault +5 more
doaj +2 more sources
Interdisciplinary Collaboration on Real World Data to Close the Knowledge Gap: A Reflection on “De Sutter et al. Predicting Volume of Distribution in Neonates: Performance of Physiologically Based Pharmacokinetic Modelling” [PDF]
PharmaceuticsThis commentary further reflects on the paper of De Sutter et al. on predicting volume of distribution in neonates, and the performance of physiologically based pharmacokinetic models We hereby stressed the add on value to collaborate on real world data ...
Karel Allegaert +2 more
doaj +2 more sources
Methods to Predict Volume of Distribution [PDF]
Current Pharmacology Reports, 2019 Prior to human studies, knowledge of drug disposition in the body is useful to inform decisions on drug safety and efficacy, first in human dosing, and dosing regimen design. It is therefore of interest to develop predictive models for primary pharmacokinetic parameters, clearance, and volume of distribution.
Kimberly, Holt +2 more
openaire +4 more sources
Distribution and Characteristics of Pancreatic Volume Using Computed Tomography Volumetry [PDF]
Healthcare Informatics Research, 2020 Objectives Changes in the pancreatic volume (PV) are useful as potential clinical markers for some pancreatic-related diseases. The objective of this study was to measure the volume of the pancreas using computed tomography (CT) volumetry and to evaluate
Jihyun Yoon +7 more
doaj +1 more source
National Journal of Physiology, Pharmacy and Pharmacology, 2015 To simplify the principles of pharmacokinetics single compartment model is designed with certain assumptions. Objectives of this model are to understand basic principles of pharmacokinetics, to represent graphically the typical natural log concentration ...
Ashishkumar Zala +2 more
doaj +1 more source
Spatial distribution of wood volume in Brazilian savannas [PDF]
Anais da Academia Brasileira de Ciências, 2019 : Here we model and describe the wood volume of Cerrado Sensu Stricto, a highly heterogeneous vegetation type in the Savanna biome, in the state of Minas Gerais, Brazil, integrating forest inventory data with spatial-environmental variables, multivariate
EDUARDA M.O. SILVEIRA +7 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Red blood cell microparticles (RMPs) is a high potency hemostatic agent, which may serve as a viable therapeutic approach. They generate thrombin in vitro and effective in arresting bleeding in animal bleeding models.
Wenche Jy +10 more
doaj +1 more source
Generalized binomial distribution in photon statistics [PDF]
, 2015 The photon-number distribution between two parts of a given volume is found for an arbitrary photon statistics. This problem is related to the interaction of a light beam with a macroscopic device, for example a diaphragm, that separates the photon flux ...
Ilyin, Aleksey V.
core +2 more sources
Tumor Volume Distributions Based on Weibull Distributions of Maximum Tumor Diameters
Applied Sciences, 2023 (1) Background: The distribution of tumor volumes is important for various aspects of cancer research. Unfortunately, tumor volume is rarely documented in tumor registries; usually only maximum tumor diameter is.
Uwe Schneider +2 more
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Distribution of Citations in one Volume of a Journal [PDF]
Interdisciplinary Description of Complex Systems, 2013 Citations to published scientific articles are regularly collected and processed, bringing about the impact factor and a large number of other bibliometric indicators.
Antonio Protić +2 more
doaj +1 more source