Results 241 to 250 of about 5,814,761 (295)
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Journal of Veterinary Pharmacology and Therapeutics, 2004
Volumes of distribution are proportionality constants between total amount of drug in the body and plasma concentrations. As snapshot plasma drug concentrations may be measured in different conditions (at equilibrium, under pseudo‐equilibrium condition,…), several volumes of distribution have been defined.
Toutain, Pierre-Louis +1 more
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Volumes of distribution are proportionality constants between total amount of drug in the body and plasma concentrations. As snapshot plasma drug concentrations may be measured in different conditions (at equilibrium, under pseudo‐equilibrium condition,…), several volumes of distribution have been defined.
Toutain, Pierre-Louis +1 more
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Cluster Computing, 1999
3D morphing is a popular technique for creating a smooth transition between two objects. In this paper we integrate volume morphing and rendering in a distributed network environment to speed up the computation efficiency. We describe our proposed system architecture of distributed volume morphing and the proposed algorithms, along with their ...
Leewen Lin, Chungnan Lee, Tong-Yee Lee
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3D morphing is a popular technique for creating a smooth transition between two objects. In this paper we integrate volume morphing and rendering in a distributed network environment to speed up the computation efficiency. We describe our proposed system architecture of distributed volume morphing and the proposed algorithms, along with their ...
Leewen Lin, Chungnan Lee, Tong-Yee Lee
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Volume‐area distributions for micropores
Journal of Applied Chemistry, 1965AbstractA comparison of micropore size distributions in the range below 100 Å has been made for a silica gel sample, using the results of exact and approximate Barrett, Joyner & Halenda computations and of the recently proposed method of Dollimore & Heal.
James P. Irving, John B. Butt
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Lung volume, volume history, and the distribution of inhaled boluses
Respiration Physiology, 1978Abstract In 8 standing men we studied the single breath washout of inhaled helium boluses. The volume at which boluses were inhaled (V B ) varied from 0% to 8% VC and subjects achieved V B both by expiring from TLC and inspiring from RV. In 3 subjects we also measured the regional distributions of inhaled Xe boluses as V B varied.
N R, Anthonisen +3 more
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1979
Every load with a drug, test substance or other material foreign to the body disturbs the natural steady state. The foreign substance enters the body by absorption from the gastrointestinal tract or an intramuscular or subcutaneous depot, by intravenous administration, or by some other route.
E. Gladtke, H. M. von Hattingberg
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Every load with a drug, test substance or other material foreign to the body disturbs the natural steady state. The foreign substance enters the body by absorption from the gastrointestinal tract or an intramuscular or subcutaneous depot, by intravenous administration, or by some other route.
E. Gladtke, H. M. von Hattingberg
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Volume of Distribution as a Function of Time
Journal of Pharmaceutical Sciences, 1976A single definition for all volume terms in pharmacokinetic modeling is proposed; this parameter is considered as a function of time. This definition will represent the kinetic nature of pharmacokinetic models and will provide a highly sensitive parameter for correlation with pharmacological responses.
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Insights on Volume of Distribution of Acids
Journal of Medicinal ChemistryAcidic drugs generally have small steady-state volumes of distribution (Vss) around 0.1-0.25 L/kg, due to high binding to serum albumin and low binding to phospholipids in tissues. Acids can reach pharmacological targets in tissues despite small Vss. Enterohepatic recirculation (EHR) of parent drug or reversible acyl glucuronide can increase the Vss of
Dennis Smith +3 more
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2009
(Vd) Apparent (hypothetical) volume of body fluid (given in L or L/kg) into which a drug would distribute at equilibrium; Vd==dose (mg/kg)/peak concentration (mg/L)=L/ kg; the Vd does not represent a real volume but is rather the size of the pool of body fluids that would be required if the drug behaves as ideal drug and is distributed equally ...
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(Vd) Apparent (hypothetical) volume of body fluid (given in L or L/kg) into which a drug would distribute at equilibrium; Vd==dose (mg/kg)/peak concentration (mg/L)=L/ kg; the Vd does not represent a real volume but is rather the size of the pool of body fluids that would be required if the drug behaves as ideal drug and is distributed equally ...
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The Distribution of Traffic Volumes
Transportation Science, 1970The distribution of hourly volumes is described and its form and characteristics are discussed. Theoretical models of the distribution are derived so that an estimate of the distribution may be obtained if only a fraction of the traffic data for the year is known.
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Volume of distribution – Again
Clinical Pharmacology in Drug Development, 2014openaire +2 more sources