Results 301 to 310 of about 6,046,760 (380)

Volume of Distribution

1979
Every load with a drug, test substance or other material foreign to the body disturbs the natural steady state. The foreign substance enters the body by absorption from the gastrointestinal tract or an intramuscular or subcutaneous depot, by intravenous administration, or by some other route.
E. Gladtke, H. M. von Hattingberg
openaire   +1 more source

Lung volume, volume history, and the distribution of inhaled boluses

Respiration Physiology, 1978
Abstract In 8 standing men we studied the single breath washout of inhaled helium boluses. The volume at which boluses were inhaled (V B ) varied from 0% to 8% VC and subjects achieved V B both by expiring from TLC and inspiring from RV. In 3 subjects we also measured the regional distributions of inhaled Xe boluses as V B varied.
N R, Anthonisen, L J, Peress, D I, Siegler, S, Dhingra   +3 more
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volume of distribution

2009
(Vd) Apparent (hypothetical) volume of body fluid (given in L or L/kg) into which a drug would distribute at equilibrium; Vd==dose (mg/kg)/peak concentration (mg/L)=L/ kg; the Vd does not represent a real volume but is rather the size of the pool of body fluids that would be required if the drug behaves as ideal drug and is distributed equally ...
openaire   +1 more source

Volume integration of fractal distribution networks

Physical Review E, 2002
An approach based on integral calculus methods is developed in order to determine the volume of a distribution network with fractal characteristics. This approach introduces alternative useful techniques and concepts to the study of the self-similarity of fractal distribution networks.
openaire   +2 more sources

Analysis of Urea Distribution Volume in Hemodialysis

Nephron, 1994
According to the urea kinetic model it is considered that the urea distribution volume (V) is that of body water, and that it is distributed in only one compartment. Since the V value is different to measure, it is normal to use 58% of body weight, in spite of the fact that it may range from 35 to 75%.
F, Maduell, F, Sigüenza, A, Caridad, F, Miralles, F, Serrato   +4 more
openaire   +2 more sources

Pharmacokinetics III: Volume of Distribution

1987
When an amount A of drug is administered intravenously (i.v.) the simple first order elimination model predicts an exponential decay with a single half life (t1/2) equal to ln(2)/K e , where K e is the rate constant for elimination. The value of ln(2) is approximately 0.693; thus, \({t_{{1 \mathord{\left/ {\vphantom {1 2}} \right.
Ronald J. Tallarida, Rodney B. Murray
openaire   +1 more source

In Silico Prediction of Volume of Distribution in Humans. Extensive Data Set and the Exploration of Linear and Nonlinear Methods Coupled with Molecular Interaction Fields Descriptors

Journal of Chemical Information and Modeling, 2016
F. Lombardo, Yankang Jing
semanticscholar   +1 more source

The Distribution of Traffic Volumes

Transportation Science, 1970
The distribution of hourly volumes is described and its form and characteristics are discussed. Theoretical models of the distribution are derived so that an estimate of the distribution may be obtained if only a fraction of the traffic data for the year is known.
openaire   +1 more source

Prediction of Clearance, Volume of distribution, and Half-life of Drugs in Extremely Low to Low Birth Weight Neonates: An Allometric Approach

European journal of drug metabolism and pharmacokinetics, 2016
I. Mahmood
semanticscholar   +1 more source

Volume of Distribution in Drug Design.

Journal of Medicinal Chemistry, 2015
Dennis A. Smith, K. Beaumont, T. Maurer, L. Di   +3 more
semanticscholar   +1 more source