Results 121 to 130 of about 4,020,070 (373)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
3D ultrasound reconstruction based on free hand acquisitions with motion estimation [PDF]
International Journal of Electronics and TelecommunicationsWe present a method for motion artifacts reduction during 3D volume reconstruction of free hand 2D ultrasound sequences. Motion estimation and additional filtering improves quality of free hand 3D ultrasound data resulting in improved imaging ...
Paweł Żogał +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Real-time external labeling layout algorithm for Direct Volume Rendering
Revista Cubana de Informática Médica, 2016 Illustrations used in technical and scientific texts often employ labels to correlate the graphic elements and their textual descriptions. Researchers have proposed several algorithms to determine the layout of the annotations on images rendered at ...
Luis Guillermo Silva Rojas +1 more
doaj +2 more sources
The VolumePro Volume Rendering Cluster: A Vital Component of Parallel End-to-End Solution [PDF]
, 2003 As data sets, both acquired from scanners and those generated from complex simulations, grow in size and complexity, researchers continue to push the boundaries of the amount of data that can be viewed, processed and analyzed interactively.
Lombeyda, Santiago, McCorquodale, John
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Volume Rendering with Advanced GPU Scheduling Strategies
, 2013 Modern GPUs are powerful enough to enable interactive display of high-quality volume data even despite the fact that many volume rendering methods do not present a natural fit for current GPU hardware.
Kainz, B +4 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Three-dimensional cinematric volume rendering technique: a novel photon-based post-processing technique for reverse right internal mammary artery/right coronary artery bypass visualization [PDF]
, 2016 Gudrun Feuchtner +3 more
openalex +1 more source