Results 161 to 170 of about 34,245 (334)

Cerebral blood flow regulation, central arterial stiffness and traumatic brain injury: Effects of aerobic exercise training

Experimental Physiology, EarlyView.
Abstract Advanced age is the strongest risk factor for Alzheimer's disease and related dementias (ADRDs). Traumatic brain injury (TBI) has also been recognized as a risk factor for ADRD, potentially contributing to an earlier onset of the disease. Thus, elucidating the mechanisms underlying brain ageing and TBI is critical for developing strategies to ...
Tsubasa Tomoto, Kan Ding, C. Munro Cullum, Rong Zhang   +3 more
wiley   +1 more source

Dosimetric Comparison of Conventional Radiotherapy, Volumetric Modulated Arc Therapy, and Proton Beam Therapy for Palliation of Thoracic Spine Metastases Secondary to Breast or Prostate Cancer [PDF]

, 2023
Anders Lideståhl, Emil Fredén, Albert Siegbahn, Gracinda Johansson, Pehr Lind   +4 more
openalex   +1 more source

Optimizing the integration of modern systemic therapies and advanced radiotherapy techniques in breast cancer management: An expert opinion from the Institut Curie Breast Radiotherapy Group

International Journal of Cancer, Volume 158, Issue 7, Page 1775-1784, 1 April 2026.
Abstract The integration of modern systemic therapies with radiotherapy (RT) represents a promising strategy in breast cancer management, enhancing both locoregional control and systemic disease outcomes. This expert consensus from the Institut Curie Breast Radiotherapy Group focuses exclusively on modern systemic agents, synthesizing current evidence ...
Cezara Cheptea, Pierre Loap, Sofiane Allali, Alain Fourquet, Kim Cao, Youlia Kirova   +5 more
wiley   +1 more source

Intensity Modulated Therapy for Patients With Breast Cancer. Practical Guidelines and Tips for an Effective Treatment Planning Strategy

Advances in Radiation Oncology
Purpose: Practical guidelines and tips for effective and robust radiation therapy treatment planning for patients with breast cancer are addressed for fixed-field intensity modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT ...
Antonella Fogliata, MSc, Hester Burger, MSc, Annemari Groenewald, PhD, Lydia Punt, MD, Jeannette Parkes, MD, Luca Cozzi, PhD   +5 more
doaj   +1 more source

Brain Dose–Volume Thresholds and Survival in Dogs With Intracranial Tumours Treated With the 10 × 4 Gy Radiotherapy Schedule: A Combined Analysis of Two Trials

Veterinary and Comparative Oncology, Volume 24, Issue 1, Page 177-185, March 2026.
ABSTRACT Dogs with intracranial tumours routinely receive radiotherapy, yet species‐specific dose–volume constraints for normal brain tissue remain undefined. In human radiation oncology, exceeding certain brain dose–volume thresholds markedly increases the risk of radiation‐induced injury (e.g., radionecrosis).
Sergejs Unterkirhers, Valeria Sabina Meier, Carla Rohrer Bley   +2 more
wiley   +1 more source

Multi‐omics predicts radiotherapy response in small cell lung cancer patients receiving whole brain irradiation

Journal of Applied Clinical Medical Physics, Volume 27, Issue 2, February 2026.
Abstract Objective Dosiomics and radiomics elaborate the low‐and high‐order features extracted from images to predict clinical outcomes. Whole‐brain radiotherapy (WBRT) has been widely used in patients with diffuse brain metastases of small cell lung cancer (SCLC).
Yifan Lei, Han Bai, Chengshu Gong, Yaoxiong Xia, Yu Hou, Ruiling Yang, Jinhui Yu, Zhe Zhang, Li Wang, Bo Li, Li Wang, Lan Li   +11 more
wiley   +1 more source

Reducing low‐dose exposure in helical TomoTherapy for locally advanced left‐sided breast cancer with a deformable image registration–based dose‐mimicking workflow

Journal of Applied Clinical Medical Physics, Volume 27, Issue 2, February 2026.
Abstract Background Helical TomoTherapy provides highly conformal dose distributions for breast irradiation but is limited by extensive low‐dose spillage (“low‐dose bath”), contributing to increased integral dose and potential long‐term toxicities. Complete blocks can suppress low‐dose spread, but at the cost of prolonged treatment times on legacy ...
Chih‐Chieh Chang, Jo‐Ting Tsai, Shih‐Ming Hsu   +2 more
wiley   +1 more source

A new strategy for volumetric-modulated arc therapy planning using AutoPlanning based multicriteria optimization for nasopharyngeal carcinoma [PDF]

, 2018
Juanqi Wang, Zhi Chen, Weiwei Li, Wei Qian, Xiaosheng Wang, Weigang Hu   +5 more
openalex   +1 more source

A feasibility study of functional preservation in craniospinal irradiation with photon for pediatric medulloblastoma

Journal of Applied Clinical Medical Physics, Volume 27, Issue 2, February 2026.
Abstract Background Craniospinal irradiation (CSI) is essential for treating pediatric medulloblastoma (MB) but causes significant long‐term toxicities. Existing dose‐reduction or partial‐sparing strategies improve neurocognitive outcomes but may compromise survival or fail to address other late effects.
Keqiang Wang, Jie Chen, Jianbo Jian, Peng Wang, Hongyang Zhang, Wenxue Zhang   +5 more
wiley   +1 more source

Preoperative Multiparametric MRI‐Based Tumour–Periprostatic Adipose Tissue Interface Characterisation for Extraprostatic Extension Prediction in Prostate Cancer

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Objective To evaluate the independent predictive value of tumour–periprostatic adipose tissue (PPAT) interface features on preoperative multiparametric magnetic resonance imaging (mpMRI) for extraprostatic extension (EPE) in prostate cancer and to compare discrimination and clinical net benefit with a baseline clinical model.
Subo Zhang, Leiming Huo, Zhitao Zhu, Jinxin Wan, Lei Xu, Jiabao Xia, Yongjun Xu, Jingfang Liu, Yan Zhao   +8 more
wiley   +1 more source