Results 221 to 230 of about 11,830 (288)

[Voluntariness of requests for assisted suicide]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Braun E, Henking T, Hempeler C, Schildmann J, Gather J.   +4 more
europepmc   +1 more source

Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis

Advanced Science, EarlyView.
Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang, Hai‐jun Liu, Yan Yue, Jun‐jie Gao, Jin Zhang, Wen‐wu Zhang, Yun‐long Zhang, Wei‐hua Lu, Sheng‐wei Jin, Pu‐hong Zhang   +9 more
wiley   +1 more source

The Morality of Assisted Dying. [PDF]

J Med Philos
Richards S.
europepmc   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Community-informed development of an in-person forum to promote breast cancer screening and research preparedness in rural and low-socioeconomic status women. [PDF]

J Clin Transl Sci
Sharma P, Imsande K, Vitriago A, Seibel M, Pritchett J, Rudder B, Tran L, Larson S, Flock C, Murphy C, Patten CA, Asiedu G, Odedina F, Lynch BA, Haddad T.   +14 more
europepmc   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

A Scalable Double‐Sided Wet Etching Strategy for Large‐Area Mushroom‐Shaped Bionic Adhesives

Advanced Science, EarlyView.
This work presents a scalable manufacturing strategy for high‐performance, large‐area, mushroom‐shaped bio‐inspired adhesives. Using a double‐sided wet etching process, the complex 3D metal molds are fabricated rapidly and controllably. The resulting adhesive structures exhibit strong, stable adhesion under various conditions, including atmosphere and ...
Keju Ji, Xinran Xu, Jian Chen, Wenjie Chen, Xiaolei Zhu, Haixiang Ma, Xingyu Jiang, Changhong Linghu, Zhendong Dai   +8 more
wiley   +1 more source

Not wanting to be a burden: wishing euthanasia to protect loved ones from the dementia. [PDF]

Palliat Care Soc Pract
Scheeres-Feitsma TM, van der Steen JT, Schaafsma P.   +2 more
europepmc   +1 more source

Training in medications for opioid use disorder and buprenorphine prescribing in the post X-waiver era: Insights from a nationwide, multispecialty survey. [PDF]

Prev Med
Kim-Vences SIH, Nguyen J, Hirth JM, Suen KP, Keough CA, Zoorob R, Kowalchuk AA.   +6 more
europepmc   +1 more source

Ethical dimensions of healthcare nudges: a PRISMA-ScR-guided scoping review and framework for responsible behavioral governance. [PDF]

Front Public Health
Shang H, Xiong L, Chen K, Tian R, Tu J, Shang X.   +5 more
europepmc   +1 more source