Arthritis &Rheumatology, Accepted Article.Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama +16 more
wiley +1 more source
Prothrombotic Activation of Platelet Pannexin‐1 Channels in Antiphospholipid Syndrome
Arthritis &Rheumatology, EarlyView.Objective ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. The objective of this study was to evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired ...
Bruna de Moraes Mazetto Fonseca +13 more
wiley +1 more source
Sociodemographic and Lifestyle Determinants of HIF-1α Response to Blood Donation and Hematopoietic Factors: Epidemiological and Public Health Perspectives from Voluntary Donors. [PDF]
Epidemiologia (Basel)Gašparović Babić S +3 more
europepmc +1 more source
Arthritis &Rheumatology, Accepted Article.Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...
Susan Manzi +12 more
wiley +1 more source
Dysregulation of U12‐Type Splicing in Lupus Neutrophils
Arthritis &Rheumatology, Accepted Article.Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco +11 more
wiley +1 more source
Knowledge, Attitude, Practice and Associated Factors Regarding Safe Blood Donation Among Students of Public Universities in Afghanistan: A Cross-Sectional Study. [PDF]
Health Sci RepNoori N, Qudrati BA, Sakhi R.
europepmc +1 more source
King Aorta: Narrative anatomy education
Anatomical Sciences Education, Volume 18, Issue 3, Page 264-276, March 2025.Abstract The aim of this study was to investigate the effects of narrative anatomy education and traditional anatomy education on academic achievement. The study included 64 students who were randomly divided into two groups. The two groups were (n = 32) control (Group 1) and (n = 32) experimental (Group 2). The pretest scores of the two groups were 36.
Halil Yilmaz
wiley +1 more source
Perspectives and attitudes to voluntary blood donation in a tertiary referral hospital blood bank
Asian Journal of Transfusion Science, 2013 Umakanth Siromani +4 more
openaire +3 more sources
HIV/AIDS and Blood Donation Policies: A Comparative Study of Public Health Policies and Individual Rights Norms [PDF]
, 2002 Hochberg, Francine A.
core +1 more source