Results 231 to 240 of about 56,042 (299)

Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib

British Journal of Clinical Pharmacology, EarlyView.
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang, Yunlan Fang, Phillip Wang, Xiang Liu, Jay Getsy, Kevin Rockich   +5 more
wiley   +1 more source

Understanding knowledge, attitude and practices of voluntary blood donations among medical students to strengthen safe transfusion practices. [PDF]

Bioinformation
Gaharwar NS, Pandey V, Mishra S, Singh A.   +3 more
europepmc   +1 more source

Fetal Tissue Transplantation: An Ethical Analysis [PDF]

, 1993
Roessler, Mark A.
core   +1 more source

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source

Blood donation practice and predictors among university and college students in Ethiopia: A systematic review and meta-analysis. [PDF]

Public Health Pract (Oxf)
Gezie H, Wuhib M, Getaneh FB, Gelaye H.
europepmc   +1 more source

Regulating the Organ Market: Normative Foundations for Market Regulation [PDF]

, 2014
Cohen, I. Glenn
core   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

Impact of shifting blood donation policy from gift to honour model: staggered difference-in-differences analysis in China.

BMJ
Liu Y, Pan Y, Zheng Z, Pan B, Zhang S, Li L, Zhao J, Wei WH, Geldsetzer P, Bärnighausen T, Chen S, Liu Z.   +11 more
europepmc   +1 more source

The Issue of Screening for Transfusion-Transmitted Infections in Sub-Saharan Africa Presents Several Challenges: A Review. [PDF]

Adv Hematol
Djientcheu Deugoue FY, Azabji-Kenfack M, Tayou Tagny C, Kouamou Tchiekou MA, Menteng Tchuente SA, Deneys V.   +5 more
europepmc   +1 more source

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

British Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia, Huang Xingxing, Jin Lu, Wang Ruwei   +3 more
wiley   +1 more source