Dysregulation of U12‐Type Splicing in Lupus Neutrophils
Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and posttranscriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron splicing ...
Luz P. Blanco +11 more
wiley +1 more source
Know your scientist: KYC as biosecurity infrastructure. [PDF]
Feldman J, Feldman T, Anton AI.
europepmc +1 more source
The Minnesota Income Tax Compliance Experiment: Replication of the Social Norms Experiment
This research note reports the results of a follow-up experiment conducted to validate an earlier experiment showing that if taxpayers overestimate the prevalence of tax evasion, their voluntary compliance can be increased by informing them about the ...
Coleman, Stephen
core
Multi‐Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis
Objective Systemic lupus erythematosus (SLE) is a multiorgan disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith +23 more
wiley +1 more source
Measuring Plantar Flexor Voluntary Activation and Maximal Voluntary Contraction in a Portable, Seated Method: A Validity and Reliability Study. [PDF]
Coventry ME +5 more
europepmc +1 more source
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu +12 more
wiley +1 more source
Structure and Function of the Achilles Tendon and Plantarflexors 1 Year Following Achilles Tendon Rupture in the United Kingdom: A Cross-Sectional Study. [PDF]
Briggs-Price S +5 more
europepmc +1 more source
Sociology of Individual Voluntary Tax Compliance
openaire +1 more source
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang +9 more
wiley +1 more source
Evolution of Quality Management in Italian Healthcare (2016-2024) Beyond Mandatory Accreditation Through the International Organization for Standardization (ISO), Joint Commission International (JCI), and the New ISO 7101 Standard: A Scoping Review. [PDF]
Fumai G +4 more
europepmc +1 more source

