Results 211 to 220 of about 85,155 (297)

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source

Timely or detailed? The impact of information disclosure on citizen co-production. [PDF]

Front Public Health
Zhang C, Liu D, Peng B.
europepmc   +1 more source

The impact of a preprescribing formative assessment on learning in final‐year medical students using hospital inpatient electronic prescribing systems

British Journal of Clinical Pharmacology, EarlyView.
Aims Graduating medical students consistently report being unprepared for the complexity of prescribing in clinical practice. Current clinical prescribing teaching and authentic assessment are limited due to patient safety concerns. We aimed to examine the educational utility of supervised preprescribing as a learning process and potential authentic ...
Kellie A. Charles, Lorna Pairman, Emily Moon, Daniel Wong, John Quayle, Tim J. Wilkinson, Matthew Doogue, Paul Chin   +7 more
wiley   +1 more source

Diagnostic errors in clinical laboratory testing process: incidence and impacts on patient safety-a 3-year voluntary incident report analysis. [PDF]

Int J Qual Health Care
Saengpattrachai M, Juntararat N, Wittayapipat U, Pimthong S, Voralertkosol T, Musikaew P, Sadangrit K, Chaiwong W.   +7 more
europepmc   +1 more source

Status of oncology drugs with a conditional approval: A cross‐sectional comparison of the Food and Drug Administration and Health Canada

British Journal of Clinical Pharmacology, EarlyView.
Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley   +1 more source

Cine Phase Contrast Magnetic Resonance Imaging of Calf Muscle Contraction in Pediatric Patients with Cerebral Palsy and Healthy Children: Comparison of Voluntary Motion and Electrically Evoked Motion. [PDF]

Children (Basel)
Weidensteiner C, Deligianni X, Haas T, Madoerin P, Bieri O, Garcia Alzamora M, Romkes J, Rutz E, Santini F, Brunner R.   +9 more
europepmc   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Mapping the regulatory landscape for environmental sustainability of medical device practices within the European Union. [PDF]

Eur J Public Health
Zarro M, Ferranti A, Garagozzo G, Fico G, Pecchia L.   +4 more
europepmc   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Building a single market for data: Data spaces as pro-competitive infrastructure. [PDF]

Data Brief
Konstantopoulou ES.
europepmc   +1 more source