Results 101 to 110 of about 690,120 (344)
Sound biosecurity systems contribute to achieving sustainable agricultural and environmental systems, reducing the threat of introducing unwanted pests and supporting food safety and product integrity.
Taylor-Hukins, Rachel +6 more
doaj +1 more source
Supporting young people: an evaluation of recent reforms to youth support services in 11 local areas [+ handout] [PDF]
This survey examines the progress made in 11 local authority areas in developing new arrangements to integrate the work of various youth support agencies.
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Sleep Alters the Velocity of Physiological Brain Pulsations in Humans
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy +13 more
wiley +1 more source
EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv +8 more
wiley +1 more source
Too Many Teens: Preventing Unnecessary Out-Of-Home Placements [PDF]
The child welfare system was created to care for abused and neglected children. But too often, teenagers are landing in the system because they simply aren't getting along with their parents.
Anne Holton, Roque Gerald, Tamara Horne
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DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su +16 more
wiley +1 more source
Dementia Friendly Kerala-the Way Forward
Dementia is a major cause of disability and dependency in old age. Compared to other Indian states, Kerala has one of the highest proportions of elderly in the country.
Sudhir Kumar +3 more
doaj
A review of homelessness and homelessness services in Weymouth and Portland [PDF]
This report reviews the nature and extent of homelessness in the Borough of Weymouth and Portland. In particular, it focuses on: Existing levels of homelessness; The causes of homelessness within the local authority area; Current service provision for ...
Cutts, Wendy +2 more
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Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li +12 more
wiley +1 more source
Good practice in projects working with prisoners' families [PDF]
The value of addressing the root causes of offending and understanding factors which encourage desistance from crime is becoming all the more apparent amongst policy makers, practitioners and academics alike.
Barry, Monica
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