Advanced Robotics Research, EarlyView.This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino +7 more
wiley +1 more source
Co-production between long-term care units and voluntary organisations in Norwegian municipalities: a theoretical discussion and empirical analysis. [PDF]
Prim Health Care Res Dev, 2020 Andfossen NB.
europepmc +1 more source
Fears, constraints, and contracts: the democratic reality for New Zealand’s community and voluntary sector [PDF]
The important role of community and voluntary sector organisations to democratic debate and policy development is widely acknowledged by governments, academics, and the sector itself.
Charles Sedgwick, Sandra Grey
core
Review of the Additional Support for Learning Act: adding benefits for learners: a report by HMIE to Scottish Ministers, November 2010 [PDF]
, 2010 Review background: "In May 2009, the Minister for Children and Early Years, gave a commitment to Parliament to establish a working group to report on how the Education (Additional Support for Learning) (Scotland) Act 2004 (the Act) is affecting ...
core
Auditory–Tactile Congruence for Synthesis of Adaptive Pain Expressions in RoboPatients
Advanced Robotics Research, EarlyView.In this work, we explore auditory–tactile congruence for synthesizing adaptive vocal pain expressions in robopatients. Using a robopatient platform that integrates vocal pain sounds with palpation forces, we conducted 7680 trials across 20 participants.
Saitarun Nadipineni +4 more
wiley +1 more source
ELABELA Targets Mitochondria to Modulate Heart Development
Advanced Science, EarlyView.The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang +22 more
wiley +1 more source
Managing reputation for ‘good works’ while undertaking commercial activities: Communication best practice guidelines for charities [PDF]
, 2010 Charities and not-for-profit organisations have traditionally eschewed commercial operations in favour of direct fund-raising from supporters. Competitive pressures, however, are driving charities to take on ‘dual citizenship’ through activity in both ...
Watson, Tom, White, Anna Marie
core
Advanced Science, EarlyView.In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu +16 more
wiley +1 more source
Advanced Science, EarlyView.A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil +7 more
wiley +1 more source
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
Advanced Science, EarlyView.ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source