Results 111 to 120 of about 61,491 (313)

Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls

American Journal of Medical Genetics Part A, Volume 197, Issue 8, August 2025.
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe, Jessica Connors, Angela Arra, Katherine Dunn, Kim Blake, Johan van Limbergen   +5 more
wiley   +1 more source

Onchocerca volvulus-specific antibody and cellular responses in onchocerciasis patients treated annually with ivermectin for 30 years and exposed to parasite transmission in central Togo

PLoS Neglected Tropical Diseases, 2022
Background Annual mass drug administrations (MDA) of ivermectin will strongly reduce Onchocerca volvulus microfilariae (mf) in the skin and in the onchocerciasis patients’ eyes. Ivermectin treatment will also affect the expression of immunity in patients,
Saskia I. Johanns, Richard G. Gantin, Bawoubadi Wangala, Kossi Komlan, Wemboo A. Halatoko, Meba Banla, Potchoziou Karabou, Adrian JF Luty, Hartwig Schulz-Key, Carsten Köhler, Peter T. Soboslay   +10 more
doaj  

Small bowel and liver/small bowel transplantation in children. [PDF]

, 1993
A clinical trial of intestinal transplantation was initiated at the University of Pittsburgh in May 1990. Eleven children received either a combined liver/small bowel graft (n = 8) or an isolated small bowel graft (n = 3).
Nour, B, Reyes, J, Starzl, TE, Todo, S, Tzakis, AG   +4 more
core  

Stage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle [PDF]

, 2016
Despite 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected.
Adam, Altschul, Altschul, Anon, Argueta, Armstrong, Armstrong, Arumugam, Babayan, Bazzocchi, Bendtsen, Benjamini, Bennuru, Bennuru, Berry, Berry, Board, Boatin, Brattig, Brattig, Brophy, Bulman, Burbelo, Burchard, Burket, Butler, Chandrashekar, Chawade, Chhabra, Choi, Claros, Constam, Cooray, Crump, Darby, Darby, Desjardins, Duckert, Edgar, Edwards, Erttmann, Finn, Franceschini, Frank, Gallin, Gardon, GBD 2013 Mortality and Causes of Death Collaborators, Geary, Ghali, Ghedin, Ghosh, Gilbert, Globisch, Godel, Gomez-Escobar, Gopal, Gotenstein, Gottsch, Grainger, Gretes, Guan, Guiliano, Hansen, Henrichfreise, Hewitson, Hewitson, Hewitson, Hotez, Hunter, Ichishita, Joseph, Joza, Kanazawa, Klion, Ko, Koonin, Korten, Krogh, Larkin, Li, Li, Liebau, Liebau, Liebau, Liebau, Littler, Liu, Longo, Lu, Lundquist, Lustigman, Lustigman, Mackenzie, Makepeace, Marti, McGarry, McSorley, Melnikow, Meyer, Michalski, Morales-Hojas, Moreno, Moreno, Morris, Mossmann, Nana-Djeunga, Nfon, Nicholson, Nomura, Ohtsuki, Ohtsuki, Osei-Atweneboana, Page, Pant, Parra, Petersen, Plaisier, Quintana, Ranjan, Rew, Rogalski, Roth, Saitou, Schulz-Key, Schulz-Key, Scocchi, Sheehan, Silva, Sommer, Srivastava, Tamarozzi, Tanikawa, Taylor, Tchakouté, Ternent, Tew, Thompson, Tiwari, Trees, Vogel, Wahl, Waterhouse, Westermann, Wildenburg, Willenbucher, Wilson, Wisniewski, Wu, Wu, Xie, Xie, Yamaguchi, Yang, Yasuda, Zanetti, Zipfel   +155 more
core   +5 more sources

The genome of Onchocerca volvulus, agent of river blindness

Nature Microbiology, 2016
Human onchocerciasis is a serious neglected tropical disease caused by the filarial nematode Onchocerca volvulus that can lead to blindness and chronic disability.
J. Cotton, S. Bennuru, A. Grote, Bhavana Harsha, A. Tracey, R. Beech, S. Doyle, M. Dunn, J. Hotopp, N. Holroyd, T. Kikuchi, Olivia J. Lambert, A. Mhashilkar, P. Mutowo, Nirvana Nursimulu, J. Ribeiro, Matthew B. Rogers, Eleanor Stanley, L. S. Swapna, Isheng. J. Tsai, T. Unnasch, D. Voronin, J. Parkinson, T. Nutman, E. Ghedin, M. Berriman, S. Lustigman   +26 more
semanticscholar   +1 more source

A Rare Case of Ileal Intussusception Caused by Primary Small Bowel Trichobezoar and Meckel's Diverticulum in an Autistic Child

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Intussusception is a condition in which one part of the intestine slides into an adjacent part of the intestine. Intussusception is an important cause of an acute abdomen and the second most common cause of bowel obstruction in children.
Marwa Messaoud, Habib Ullah Joya, Amani N. Alansari, Abir Jouini, Amine Ksiaa, Ahmed Zrig, Lasaad Sahnoun   +6 more
wiley   +1 more source

PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection

European Journal of Immunology, Volume 55, Issue 8, August 2025.
During filarial nematode infection with Litomosoides sigmodontis, PD‐L2 down‐regulates Th2 cell expression of GATA‐3 and Th2 cytokines and enables parasite survival. Concurrently, B cells suppress protective immunity through a mechanism that does not involve PD‐L2.
Johanna A. Knipper, Sharon M. Campbell, Judith E. Allen, Matthew D. Taylor   +3 more
wiley   +1 more source

Evidence against Wolbachia symbiosis in Loa loa [PDF]

, 2003
BACKGROUND: The majority of filarial nematode species are host to Wolbachia bacterial endosymbionts, although a few including Acanthocheilonema viteae, Onchocerca flexuosa and Setaria equina have been shown to be free of infection. Comparisons of species
Akue, Jean-Paul, Beeching, Nick J, Bianco, Albert E, Egerton, Gill, Enyong, Peter, Hoerauf, Achim, Kläger, Sabine L, McGarry, Helen F, Pfarr, Ken, Taylor, Mark J, Wanji, Samuel   +10 more
core   +2 more sources

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity

bioRxiv, 2016
Background Treatment of onchocerciasis using mass ivermectin administration has reduced morbidity and transmission throughout Africa and Central/South America.
S. Doyle, Catherine Bourguinat, H. Nana-Djeunga, Jonas A Kengne-Ouafo, S. Pion, J. Bopda, J. Kamgno, S. Wanji, H. Che, A. Kuesel, M. Walker, M. Basáñez, D. Boakye, M. Osei-Atweneboana, M. Boussinesq, R. Prichard, W. Grant   +16 more
semanticscholar   +1 more source

Long‐term home parenteral nutrition in chronic intestinal failure following metabolic and bariatric surgery and its clinical outcomes: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, Volume 49, Issue 6, Page 773-782, August 2025.
Abstract Background Metabolic and bariatric surgery is one of the most efficacious treatments for obesity. The increasing incidence of referrals to intestinal rehabilitation programs and the necessity for long‐term parenteral nutrition because of bariatric surgery complications have gained attention, yet data remain limited.
Dane Christina Daoud, Katherine J. P. Schwenger, Yasaman Ghorbani, Leah Gramlich, George Ou, David Armstrong, Maitreyi Raman, Johane P. Allard, Barbara Bielawska   +8 more
wiley   +1 more source