Results 131 to 140 of about 602,787 (351)

Early skeletal muscle deconditioning and reduced exercise capacity during (neo)adjuvant chemotherapy in patients with breast cancer

open access: yesCancer, Volume 129, Issue 2, Page 215-225, 15 January 2023., 2023
Abstract Background Fatigue is a hallmark of breast cancer and is associated with skeletal muscle deconditioning. If cancer‐related fatigue occurs early during chemotherapy (CT), the development of skeletal muscle deconditioning and its effect on exercise capacity remain unclear. The aim of this study was to investigate the evolution of skeletal muscle
Joris Mallard   +9 more
wiley   +1 more source

Associations between Nausea, Vomiting, Fatigue and Health-Related Quality of Life of Women in Early Pregnancy: The Generation R Study

open access: yesPLoS ONE, 2016
The objective of this study was to evaluate the independent associations between nausea, vomiting, fatigue and health-related quality of life of women in early pregnancy in the Generation R study, which is a prospective mother and child cohort.
Guannan Bai   +5 more
semanticscholar   +1 more source

Postnatal Progressive Craniosynostosis: An Unusual Case Presentation Leading to Cascade Diagnosis for Multiple Generations

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT NM_000141.5: FGFR2 c.1032G>A is a pathogenic variant that causes Crouzon syndrome through activation of a new donor splice site. This clinical report highlights the intrafamilial variability that can exist with this specific variant. The proband is a 4‐year‐old boy who initially presented with concern for seizures.
Jessica T. Ogawa   +3 more
wiley   +1 more source

Radiosensitization of calreticulin‐overexpressing human glioma cell line by the polyphenolic acetate 7, 8‐diacetoxy‐4‐methylcoumarin

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background Calreticulin (CRT), an endoplasmic reticulum–resident protein generally overexpressed in cancer cells, is associated with radiation resistance. CRT shows higher transacetylase activity, as shown by us earlier, in the presence of the polyphenolic acetates (like 7, 8‐diacetoxy‐4‐methylcoumarin, DAMC) and modifies the activity of a ...
Amit Verma   +6 more
wiley   +1 more source

New Onset Thyrotoxicosis Presenting as Vomiting, Abdominal Pain and Transaminitis in the Emergency Department

open access: yesWestern Journal of Emergency Medicine, 2007
This case report describes an unusual presentation of an emergency department (ED) patient with nausea, vomiting, and epigastric pain, who was initially diagnosed with viral hepatitis.
Gharahbaghian, Laleh   +4 more
doaj  

Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe   +5 more
wiley   +1 more source

Nausea and vomiting in gastroparesis: similarities and differences in idiopathic and diabetic gastroparesis

open access: yesNeurogastroenterology and Motility, 2016
Nausea and vomiting are classic symptoms of gastroparesis. It remains unclear if characteristics of nausea and vomiting are similar in different etiologies of gastroparesis.
H. Parkman   +16 more
semanticscholar   +1 more source

Potential New Expression Biomarkers for Anorexia Nervosa

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Anorexia nervosa (AN) is a psychiatric disorder with an estimated heritability of around 70%. Although the largest meta‐analysis of genome‐wide association studies on AN identified independent risk‐conferring loci for the disorder, the molecular mechanisms underlying the genetic basis of AN remain to be elucidated.
Camille Verebi   +8 more
wiley   +1 more source

Urinary excretion profile of prednisolone and prednisone after rectal administration: Significance in antidoping analysis

open access: yesDrug Testing and Analysis, Volume 14, Issue 11-12, Page 2007-2016, November-December 2022., 2022
In this work, excretion profile of prednisone and prednisolone was evaluated in subjects in therapy with glucocorticoids‐based rectal formulations. The absorption rate and the systemic bioavailability of an active principle after rectal administration are strongly influenced by the type of formulations and the physiological conditions of the absorption
Loredana Iannella   +6 more
wiley   +1 more source

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