Results 131 to 140 of about 457,294 (313)

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal   +6 more
wiley   +1 more source

24 GASTROINTESTINAL (GI) MOTILITY, DUODENOGASTRIC REFLUX (DGR) AND GASTRIC EMPTYING (GE) IN CHILDREN WITH CHRONIC VOMITING [PDF]

open access: bronze, 1988
Salvatore Cucchiara   +4 more
openalex   +1 more source

Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa   +15 more
wiley   +1 more source

Non‐Syndromic Tumefactive Demyelinating Lesions in the Pediatric Population: Four Case Reports and Review of the Literature

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Tumefactive demyelinating lesions (TDLs) are large lesions (> 2 cm) seen in demyelinating syndromes such as multiple sclerosis, myelin oligodendrocyte glycoprotein antibody‐associated disorder, and neuromyelitis optica spectrum disorder. They rarely occur in children and most often have a monophasic course.
Elizabeth C. Ballinger   +6 more
wiley   +1 more source

Etiologies of Cyclic Vomiting Syndrome in Children: A Systematic Review of 1,373 Patients. [PDF]

open access: yesPediatr Gastroenterol Hepatol Nutr
Waisfeld A   +4 more
europepmc   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye   +8 more
wiley   +1 more source

Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision Framework

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Radiolabeled human mass balance studies are crucial for identifying circulating metabolites and understanding drug absorption, excretion, and clearance pathways. Metabolite profiling involves quantifying all drug‐related entities, including parent drug and metabolites in plasma and excreta, using extended liquid chromatography methods coupled with ...
Filip Cuyckens   +21 more
wiley   +1 more source

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