Role of gemcitabine in the treatment of advanced and metastatic breast cancer [PDF]
Gemcitabine is an antimetabolite drug with proven antitumor activity and tolerability in metastatic breast cancer. In a total of nine studies, gemcitabine monotherapy has reached response rates of up to 37% in the first-line setting, 26% in the second ...
Heinemann, Volker
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ABSTRACT Objective There is limited consensus on endoscopic skull base surgery (ESBS) reconstruction principles. This study aims to generate comprehensive themes regarding ESBS reconstruction by pooling the experiences of ESBS experts, with comparison to a literature review of current published evidence.
Edward C. Kuan+77 more
wiley +1 more source
A 6½‐year‐old girl was diagnosed with a medulloblastoma, SHH activated, subtype 3 and TP53 mutant (somatic). After surgery and chemotherapy, she was monitored with quarterly magnetic resonance imaging (MRI) scans and remained free of disease for almost 4 years.
Daniel Antunes Moreno+19 more
wiley +1 more source
Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in Zambia. [PDF]
In the Maheba Refugee Settlement, in the clinics supported by Medecins Sans Frontieres, all children aged up to 5 years with a confirmed diagnosis of uncomplicated falciparum malaria are treated with the combination of sulfadoxine/pyrimethamine (SP) and ...
Bloland PB+9 more
core +2 more sources
μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim+6 more
wiley +1 more source
The comparison effect of ondansetron and Metoclopramide in thereducing of nausea and vomitting after loparoscopic cholescistectomy [PDF]
Background: Postoperative nausea and vomiting (PONV) is a side effect of anesthesia. Without prophylactic intervention, PONV by about one-third of patients (10 to 60%) under general anesthesia occurs. PONV consequences include delayed discharge from PACU
انتظاری, مسعود+2 more
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Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou+4 more
wiley +1 more source
The Comparison Effect of Preoperative Ondansetron and Metoclopramide in Reducing Nausea and Vomitting after Loparoscopic Cholecystectomy [PDF]
Background & Objectives: Postoperative nausea and vomiting (PONV) is one of the most common complications of anesthesia and without prophylactic intervention occurs in about one-third of patients under general anesthesia.
انتظاری, مسعود+2 more
core
Acupressure to Reduce Treatment-Related Symptoms for Children With Cancer and Recipients of Hematopoietic Stem Cell Transplant: Protocol for a Randomized Controlled Trial. [PDF]
BackgroundWe describe the study design and protocol of a pragmatic randomized controlled trial (RCT) Acupressure for Children in Treatment for a Childhood Cancer (ACT-CC).ObjectiveTo describe the feasibility and effectiveness of an acupressure ...
Adcock, Robyn+12 more
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