Results 21 to 30 of about 9,530,886 (208)

[von Hippel-Lindau disease].

Bratislavske lekarske listy, 1993
The available diagnostic and therapeutic possibilities allow to treat successfully all manifestations of von Hippel-Lindau disease. Adenocarcinomas of the kidneys, however, still present a serious therapeutic problem due to their mostly bilateral and multifocal occurrence.
O, Masek, V, Krislo
openaire   +2 more sources

Management of a Case of von Hippel-Lindau for Coronary Artery Bypass Grafting

The Indian Anaesthetists' Forum, 2015
von Hippel-Lindau (VHL) disease is a rare autosomal dominant genetic disorder with retinal and nervous system haemangioblastomas, phaeochromocytoma, renal, pancreatic and endolymphatic tumours.
Geetanjali S. Verma
doaj   +1 more source

Von Hippel–Lindau disease [PDF]

, 2015
von Hippel-Lindau (VHL) disease is an inheritable condition with an incidence of 1 in 36000 live births. Individuals with VHL develop benign and malignant tumors including retinal and central nervous system hemangioblastomas, clear cell renal cell carcinomas (RCC), pheochromocytomas, pancreatic neuroendocrine tumors and endolymphatic sac tumors (ELSTs).
Prashant, Chittiboina, Russell R, Lonser
  +5 more sources

Von Hippel-Lindau's Disease [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1976
SUMMARY:A patient with Von Hippel-Lindau's disease was followed from the time of diagnosis to the time of his death 13 years later. He was asymptomatic when the diagnosis was made, although a hemangioblastoma of the medulla was found on angiography. The patient's course and autopsy are described and the features of this disease are reviewed.
R G, Miller, R J, Porter, S L, Nielsen, H, Hosobuchi   +3 more
openaire   +2 more sources

[Von Hippel-Lindau disease]. [PDF]

Nederlands tijdschrift voor geneeskunde, 2000
Von Hippel-Lindau disease (VHL) is an autosomal dominant inherited cancer syndrome. The disease was diagnosed in three patients: a 22-year-old woman who presented with decreased vision due to retinal angiomatosis and in whom a renal carcinoma was diagnosed five years later at a routine VHL analysis, a man aged 44 who died with bilateral renal cysts and
Los, M., Links, T, Lenders, J.W., Voest, E.E.   +3 more
openaire   +5 more sources

Von Hippel–Lindau Disease [PDF]

Journal of Pediatric Genetics, 2016
Von Hippel-Lindau disease is an autosomal dominant syndrome which occurs secondary to germline mutations in the VHL tumor suppressor gene, located on chromosome 3. Clinically von Hippel-Lindau disease is characterized by an increased risk of developing simple visceral cysts, most commonly in the pancreas and kidneys, in addition to an increased risk of
Jennifer J, Findeis-Hosey, Kelly Q, McMahon, Sarah K, Findeis   +2 more
openaire   +3 more sources

Laparoscopic partial adrenalectomy for bilateral pheochromocytomas in a boy with von Hippel-Lindau disease [PDF]

, 2000
Objectives: In adults, increasing numbers of adrenalectomies for pheochromocytomas are performed laparoscopically. We report for the first time laparoscopic bilateral subtotal adrenalectomy for pheochromocytomas in an 8-year-old boy with von Hippel ...
Elsner, Romy, Neumann, Hartmut, Janetschek, Günter, Neumann, Hartmut P. H., Radmayr, Christian, Bartsch, Georg   +5 more
core   +1 more source

Isolated familial pheochromocytoma as a variant of von Hippel-Lindau disease. [PDF]

, 1996
Inherited pheochromocytomas are often part of familial syndromes, especially multiple endocrine neoplasia type 2 (MEN 2), retinal cerebellar hemangioblastomatosis [von Hippel-Lindau (vHL) disease] or neurofibromatosis type 1.
Crossey, P.A., Höppner, W., Engelhardt, D., Maher, E.R., Ritter, M.M., Frilling, A., Mulligan, L., Ponder, B.A.J.   +7 more
core   +1 more source

Von Hippel-Lindau disease

International Journal of Surgery Case Reports, 2022
ABSTRACT Introduction and importance: Von Hippel-Lindau (VHL) disease is a rare autosomal dominantly inherited genetic condition. Von Hippel characterized the illness independently in 1911, and Lindau in 1926. Its prevalence is estimated to be about 1 in every 36,000 live births.
Neupane, Durga, Dahal, Alok, Lageju, Nimesh, Jaiswal, Lokesh Shekher, Kandel, Ashim, Manandhar, Srista   +5 more
openaire   +2 more sources

Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von hippel-lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinities [PDF]

, 2014
E3 ubiquitin ligases are attractive targets in the ubiquitin-proteasome system, however, the development of small-molecule ligands has been rewarded with limited success.
Dias, David M, Carles Galdeano (1305135), Galdeano, Carles, Dias, David M., David M. Dias (1340694), Van Molle, Inge, Gadd, Morgan Stuart, Ciulli, Alessio, Sarah Hewitt (1340700), Soares, Pedro, Galdeano , Carles, Pedro Soares (393566), Gadd, Morgan S., Salvatore Scaffidi (1340703), Inge Van Molle (1284120), Morgan S. Gadd (149371), Scaffidi, Salvatore, Ipek Birced (1340697), Alessio Ciulli (762789), Hewitt, Sarah, Birced, Ipek   +20 more
core   +1 more source