Results 111 to 120 of about 146,739 (334)

Haemophilia Prophylaxis in the Age of Innovation: Exploring Opportunities for Personalized Treatment

Haemophilia, EarlyView.
ABSTRACT Introduction Recent advancements in haemophilia treatment have introduced a range of innovative therapies, including activated FVIII mimetics, ultra‐extended half‐life recombinant FVIII, rebalancing agents and gene therapy. These developments have transformed treatment options and expanded prophylaxis strategies.
Yesim Dargaud, Fabienne Volot, Stephanie Desage, Claire Pouplard, Valerie Chamouard, Anne Lienhart   +5 more
wiley   +1 more source

Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin. [PDF]

, 1987
Scott D. Berkowitz, J Dent, James R. Roberts, Yoshihiro Fujimura, EF Plow, Koiti Titani, Zaverio M. Ruggeri, T S Zimmerman   +7 more
openalex   +1 more source

Physical Activity Awareness and Understanding of Treatment Protection Among People With Haemophilia and Their Caregivers in Central Europe

Haemophilia, EarlyView.
ABSTRACT Background Physical activity is now considered generally beneficial for persons with haemophilia (PWH). However, the specific type and extent of activity and its impact on quality of life (QoL) and bleed protection during exercise is under‐researched.
Angelika Batorova, Atanas Banchev, Ana Boban, Brigitte Brand, Melen Brinza, Barbara Faganel Kotnik, Csongor Kiss, Gediminas Puras, Jan Rajnoch, Ester Zapotocka   +9 more
wiley   +1 more source

von Willebrand's disease characterized by increased ristocetin sensitivity and the presence of all von Willebrand factor multimers in plasma [PDF]

, 1986
Lars Holmberg, Erik Berntorp, Mikael Donnér, Nilsson Im   +3 more
openalex   +1 more source

European Principles of Nursing Care for Persons With Inherited Bleeding Disorders

Haemophilia, EarlyView.
ABSTRACT Introduction A nurse is one of the core members of the multidisciplinary haemophilia team. However, what people with inherited bleeding disorders (PwBD) can expect from them has not yet been formally defined. Aim This project, initiated by the EAHAD Nurses Committee, aimed to establish Principles of Nursing Care (PoNC) for PwBD to promote high‐
Nanda Uitslager, Mary Kavanagh, Maj Birkedal, Linda Myrin‐Westesson, the EAHAD Nurses Committee   +4 more
wiley   +1 more source

In vivo interaction of von Willebrand factor with platelets following cryoprecipitate transfusion in platelet-type von Willebrand's disease [PDF]

, 1984
JL Miller, BD Boselli, JM Kupinski
openalex   +1 more source

Outcomes of Dental Treatment Procedures in People With Haemophilia Treated Under a Comprehensive Care Model: An Analysis of Cases From a Tertiary Care Centre

Haemophilia, EarlyView.
ABSTRACT Background Haemophilia is a chronic, lifelong bleeding disorder that requires interdisciplinary care to manage and mitigate the disease burden throughout a patient's life. There is no universally accepted protocol for managing haemophilia patients during dental care.
Mathangi Kumar, Sulochana Badagabettu, Keerthilatha M. Pai, Annamma Kurien, Archana MV, Shreemathi S. Mayya, Sreejith Govindan   +6 more
wiley   +1 more source

Decreased plasma ADAMTS-13 activity as a predictor of postoperative bleeding in cyanotic congenital heart disease

Clinics, 2013
OBJECTIVE: To analyze the preoperative plasma antigenic concentration and activity of von Willebrand factor and its main cleaving protease ADAMTS-13 in pediatric patients with cyanotic congenital heart disease undergoing surgical treatment and ...
Rosangela P.S. Soares, Sérgio P. Bydlowski, Marcelo B. Jatene, Janete Ferreira Hironaka, Antonio Augusto Lopes   +4 more
doaj  

Type IIB von Willebrand's disease: differential clearance of endogenous versus transfused large multimer von willebrand factor [PDF]

, 1982
ZM Ruggeri, R Lombardi, L Gatti, R Bader, C Valsecchi, TS Zimmerman   +5 more
openalex   +1 more source

Profiling of Anti‐FVIII Antibodies in Acquired Haemophilia A: ‘Insights into Domain Specificity, Isotype Variability, and Clinical Correlations’

Haemophilia, EarlyView.
ABSTRACT Introduction Acquired haemophilia A (AHA) is a rare autoimmune disorder caused by autoantibodies against coagulation factor VIII (FVIII), resulting in significant bleeding risks. Aim To characterize the anti‐FVIII antibody profile in AHA patients by assessing isotypes, subclasses, and correlations with key clinical parameters.
Ann‐Cristin Berkemeier, Isabell Matuschek, Katrin Hartlieb, Thilo Albert, Natascha Marquardt, Johannes Oldenburg, Behnaz Pezeshkpoor   +6 more
wiley   +1 more source