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Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]
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Pump‐Induced Hemolysis of Speed Modulated Axial‐Flow Left Ventricular Assist Devices
Two Sputnik1 and two HeartMate2 axial‐flow LVADs were operated in hemolysis test benches under both constant speed and speed modulation modes (n = 7). One of the Sputnik1 pumps exhibited a statistically significant increase in hemolysis, while none of the HeartMate2 pumps showed statistically significant differences.
Patrick Borchers+3 more
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Abstract Aim Hepatorenal syndrome‐induced acute kidney injury (AKI) comprises AKI and liver cirrhosis (LC) and is a risk factor for poor prognoses of patients with LC. Decreased a disintegrin‐like metalloproteinase with thrombospondin type 1 motif 13 (ADAMTS13) activity and increased von Willebrand factor (vWF) antigen levels are associated with LC ...
Masayoshi Takami+9 more
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Dexmedetomidine Reduces Chronic Stress–Related Thrombosis in a Mouse FeCl3 Model
Schematic summary of the mechanism by which dexmedetomidine prevents chronic stress–related carotid artery thrombosis in a mouse FeCl3 model. These findings present evidence and a potential mechanistic explanation of the Dex‐mediated amelioration of arterial thrombosis associated with the reduction of oxidative stress, inflammation, and apoptosis, and ...
Huazhen Wang+11 more
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New England Journal of Medicine, 2016
Von Willebrand's disease is the most common inherited bleeding disorder and is generally transmitted as an autosomal dominant trait. It is mainly associated with mucosal bleeding and excessive bleeding after trauma or surgery. A variety of effective treatments are available.
Leebeek, F.W.G., Eikenboom, J.C.J.
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Von Willebrand's disease is the most common inherited bleeding disorder and is generally transmitted as an autosomal dominant trait. It is mainly associated with mucosal bleeding and excessive bleeding after trauma or surgery. A variety of effective treatments are available.
Leebeek, F.W.G., Eikenboom, J.C.J.
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Pediatric Clinics of North America, 2008
von Willebrand disease is a common inherited bleeding disorder and many cases are diagnosed in childhood. It has a negative impact on the quality of life of affected individuals; therefore, it is important that the condition be recognized and diagnosed.
Jeremy Robertson+2 more
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von Willebrand disease is a common inherited bleeding disorder and many cases are diagnosed in childhood. It has a negative impact on the quality of life of affected individuals; therefore, it is important that the condition be recognized and diagnosed.
Jeremy Robertson+2 more
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von Willebrand disease and von Willebrand factor
Haemophilia, 2022AbstractSummaryProgress in both basic and translational research into the molecular mechanisms of VWD can be seen in multiple fields.Genetics of VWDIn the past several decades, knowledge of the underlying pathogenesis of von Willebrand disease (VWD) has increased tremendously, thanks in no small part to detailed genetic mapping of the von Willebrand ...
Brooke, Sadler+2 more
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Human Pathology, 1987
von Willebrand disease (vWD) is a bleeding disorder characterized by a complex hemostatic defect. Abnormal platelet function, usually reflected by a prolonged bleeding time, is the result of a quantitative or qualitative defect of von Willebrand factor (vWF).
Theodore S. Zimmerman+1 more
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von Willebrand disease (vWD) is a bleeding disorder characterized by a complex hemostatic defect. Abnormal platelet function, usually reflected by a prolonged bleeding time, is the result of a quantitative or qualitative defect of von Willebrand factor (vWF).
Theodore S. Zimmerman+1 more
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Pediatric Blood & Cancer, 2012
AbstractLong‐term prophylaxis is not as well known in Von Willebrand disease (VWD) as in hemophilia but attempts to evaluate prophylaxis scientifically in VWD have started. A few cohort studies have been reported. In an international effort the Von Willebrand disease prophylaxis network (VWD PN) has been formed to investigate the role of prophylaxis in
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AbstractLong‐term prophylaxis is not as well known in Von Willebrand disease (VWD) as in hemophilia but attempts to evaluate prophylaxis scientifically in VWD have started. A few cohort studies have been reported. In an international effort the Von Willebrand disease prophylaxis network (VWD PN) has been formed to investigate the role of prophylaxis in
openaire +3 more sources