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Treatment of von Willebrand's disease
Journal of Internal Medicine, 1997von Willebrand's disease is the most frequent of inherited bleeding disorders (1:100 affected individuals in the general population). The aim of therapy is to correct the dual defects of haemostasis, i.e. abnormal coagulation expressed by low levels of factor VIII and abnormal platelet adhesion expressed by a prolonged bleeding time. There are two main
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Antibodies to von Willebrand factor in von Willebrand disease
1995The occurrence of an alloantibody directed against von Willebrand factor in a multitransfused patient with severe (type III) von Willebrand disease was first reported in 2 consecutive studies by Sarji et al. (1974) and Stratton et al. (1975). After this, 14 additional cases of alloantibodies were described and reviewed by Mannucci and Mari (1984).
Pier Mannuccio Mannucci +1 more
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2018
Von Willebrand disease (vWD) is the most common bleeding disorder in humans. It is the result of an abnormality in the amount, structure, or function of von Willebrand factor (vWF), a glycoprotein important in maintaining normal hemostasis.. In children with vWD, the most frequent presentation is easy bruising and epistaxis.
Nina A. Guzzetta, Laura A. Downey
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Von Willebrand disease (vWD) is the most common bleeding disorder in humans. It is the result of an abnormality in the amount, structure, or function of von Willebrand factor (vWF), a glycoprotein important in maintaining normal hemostasis.. In children with vWD, the most frequent presentation is easy bruising and epistaxis.
Nina A. Guzzetta, Laura A. Downey
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2020
von Willebrand disease (VWD), the most common inherited bleeding disorder, is caused by quantitative or qualitative deficiencies in the von Willebrand factor (VWF) protein. VWF is crucial for platelet adhesion and aggregation at sites of vessel injury and also for stabilizing and transporting factor VIII (FVIII) to these sites.
Lakshmi Srivaths, Trinh T Nguyen
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von Willebrand disease (VWD), the most common inherited bleeding disorder, is caused by quantitative or qualitative deficiencies in the von Willebrand factor (VWF) protein. VWF is crucial for platelet adhesion and aggregation at sites of vessel injury and also for stabilizing and transporting factor VIII (FVIII) to these sites.
Lakshmi Srivaths, Trinh T Nguyen
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2013
Abstract The interactions between clinical and laboratory medicine moving to and from bedside, bench, and back to bedside are no more apparent than in our unraveling of von Willebrand Disease. Discovered nearly a century ago, we are still expanding both our clinical and laboratory knowledge of this disorder.
Margaret E. Rick, Barbara A. Konkle
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Abstract The interactions between clinical and laboratory medicine moving to and from bedside, bench, and back to bedside are no more apparent than in our unraveling of von Willebrand Disease. Discovered nearly a century ago, we are still expanding both our clinical and laboratory knowledge of this disorder.
Margaret E. Rick, Barbara A. Konkle
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Onconephrology: The intersections between the kidney and cancer
Ca-A Cancer Journal for Clinicians, 2021Mitchell H Rosner +2 more
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