Results 291 to 300 of about 185,950 (370)

Impact of Underlying Portal Hypertension on Severity and Course of Acute‐On‐Chronic Liver Failure

open access: yesLiver International, Volume 45, Issue 10, October 2025.
ABSTRACT Background and Aims The impact of portal hypertension (PH) during acute‐on‐chronic liver failure (ACLF) remains unclear. This study investigated the link between underlying PH severity, systemic inflammation (SI), and the course of ACLF. Methods Consecutive patients with ACLF (n = 192) who met the EASL‐CLIF criteria were retrospectively ...
Vlad Taru   +11 more
wiley   +1 more source

Rare onset of congenital thrombotic thrombocytopenic purpura during pregnancy: A novel ADAMTS13 gene variant

open access: yesTransfusion, Volume 65, Issue 10, Page 1982-1988, October 2025.
Abstract Background Congenital thrombotic thrombocytopenic purpura (cTTP) is a rare autosomal recessive thrombotic microangiopathy caused by biallelic mutations in ADAMTS13, leading to severe enzyme deficiency. The absence of ADAMTS13 prevents cleavage of ultra‐large von Willebrand factor multimers, resulting in platelet‐rich microthrombi formation ...
Rita González‐Resina   +6 more
wiley   +1 more source

Reduced von Willebrand factor survival in type Vicenza von Willebrand disease

open access: bronze, 2002
Alessandra Casonato   +6 more
openalex   +1 more source

Development and Validation of a Liquid Chromatography High‐Resolution Mass Spectrometry Method for Blood Desmopressin Quantification and Its Application in Hemophilia A Patients

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 18, 30 September 2025.
ABSTRACT Desmopressin (DDAVP), which indirectly increases Coagulation Factor VIII concentrations in the blood, is a common treatment for bleeding disorders such as von Willebrand disease or hemophilia A. However, DDAVP exhibits significant variability in response due to interindividual differences in pharmacokinetics.
Sophie Hodin   +7 more
wiley   +1 more source

von Willebrand disease and heavy menstrual bleeding: when and how to test. [PDF]

open access: yesHematology Am Soc Hematol Educ Program
Perez Botero J.
europepmc   +1 more source

Ascitic fluid concentrations of fibronectin and cholesterol [PDF]

open access: yes, 1990
Gerbes, Alexander L.   +3 more
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