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Antibodies to von Willebrand factor in von Willebrand disease
1995The occurrence of an alloantibody directed against von Willebrand factor in a multitransfused patient with severe (type III) von Willebrand disease was first reported in 2 consecutive studies by Sarji et al. (1974) and Stratton et al. (1975). After this, 14 additional cases of alloantibodies were described and reviewed by Mannucci and Mari (1984).
Pier Mannuccio Mannucci +1 more
openaire +3 more sources
2020
von Willebrand disease (VWD), the most common inherited bleeding disorder, is caused by quantitative or qualitative deficiencies in the von Willebrand factor (VWF) protein. VWF is crucial for platelet adhesion and aggregation at sites of vessel injury and also for stabilizing and transporting factor VIII (FVIII) to these sites.
Lakshmi Srivaths, Trinh T Nguyen
openaire +2 more sources
von Willebrand disease (VWD), the most common inherited bleeding disorder, is caused by quantitative or qualitative deficiencies in the von Willebrand factor (VWF) protein. VWF is crucial for platelet adhesion and aggregation at sites of vessel injury and also for stabilizing and transporting factor VIII (FVIII) to these sites.
Lakshmi Srivaths, Trinh T Nguyen
openaire +2 more sources
2013
Abstract The interactions between clinical and laboratory medicine moving to and from bedside, bench, and back to bedside are no more apparent than in our unraveling of von Willebrand Disease. Discovered nearly a century ago, we are still expanding both our clinical and laboratory knowledge of this disorder.
Margaret E. Rick, Barbara A. Konkle
openaire +2 more sources
Abstract The interactions between clinical and laboratory medicine moving to and from bedside, bench, and back to bedside are no more apparent than in our unraveling of von Willebrand Disease. Discovered nearly a century ago, we are still expanding both our clinical and laboratory knowledge of this disorder.
Margaret E. Rick, Barbara A. Konkle
openaire +2 more sources