Results 111 to 120 of about 5,479,866 (221)

von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.

, 1998
BACKGROUND Thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome are severe microvascular disorders of platelet clumping with similar signs and symptoms.
Furlan M, Krause M, Scharrer I, Solenthaler M, Remuzzi G, Mittler U, Kyrle PA, Brenner B, Robles R, Lämmle B, Galbusera M, Aumann V   +11 more
core   +1 more source

Plasma Exchange for Hantavirus Pulmonary Syndrome: A Mechanistic Case for an Untested Intervention

Journal of Clinical Apheresis, Volume 41, Issue 5, October 2026.
ABSTRACT Hantavirus pulmonary syndrome (HPS) carries a case fatality rate of 35%–40% and has no approved pharmacologic treatment. Its pathophysiology is rooted in the plasma compartment: cytokines, viral antigens, immune complexes, and platelet‐binding glycoproteins circulate as drivers of immunopathologic endothelial injury, noncardiogenic pulmonary ...
Menatalla Nadim, Yasamin Mirzabeigi, Yamac Akgun   +2 more
wiley   +1 more source

Pediatric Essential Thrombocythemia With a Novel CALR Mutation: A Case Report

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Pediatric essential thrombocythemia (ET) is extremely rare and frequently lacks identifiable driver mutations. We report a case of a 5‐year‐old male with ET harboring a novel CALR exon 9 frameshift mutation complicated by acquired von Willebrand syndrome.
Kana Tsuji, Suguru Uemura, Tomoko Fujikawa, Nobuyuki Yamamoto, Aiko Kozaki, Atsuro Saito, Toshiaki Ishida, Takeshi Mori, Makiko Yoshida, Takahiro Okutani, Daiichiro Hasegawa   +10 more
wiley   +1 more source

Bleeding Complications in JAK2‐Variant Essential Thrombocythemia: A Revisit in 2025

eJHaem
Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterised by sustained thrombocytosis. Paradoxically, bleeding complications remain an under‐recognised clinical challenge. Compared with CALR‐mutated patients, those harbouring the JAK2‐
Gerard Gurumurthy, Samantha Gurumurthy, Tim C. P. Somervaille, Anna Falanga, Jecko Thachil   +4 more
doaj   +1 more source

¿ES POSIBLE TENER UN PARTO SEGURO CON UNA COAGULOPATÍA?

Revistas Argentina de Medicina, 2018
Una mujer de 20 años acudió al consultorio por amenorrea de dos meses de evolución, se le realizó una ecografía transvaginal y se le diagnosticó gestación única más hematoma subcoriónico.
Francesca Cordano Lozano, Diego Bustamante Heinhson, Juan Francisco Sánchez Chiroque, Víctor Manuel Parra Gutiérrez   +3 more
doaj   +2 more sources

Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease

MedComm, Volume 7, Issue 10, October 2026.
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang, Fangjiaqi Wei, Mengdi Qu, Yuwen Shao, Tingye Xu, Darko Stojkov, Hans‐Uwe Simon, Ben Huang, Changhong Miao, Hao Zhang   +9 more
wiley   +1 more source

Small Proteoglycans, Big Impact: Decorin, Biglycan, and Asporin in Musculoskeletal Tissue Health and Disease

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT The extracellular matrix (ECM) is a dynamic and information‐rich network that integrates structural support with biochemical and mechanical signaling. Among its key regulatory components are the Small Leucine‐Rich Proteoglycans (SLRPs), a family of matrix molecules that coordinate extracellular architecture with cell signaling.
Alessandra Leone, Zsuzsa Jenei‐Lanzl, Frank Zaucke   +2 more
wiley   +1 more source

Small Bowel Lesions and Bleeding Risk in Hemodialysis Patients: A Narrative Review

Hemodialysis International, Volume 30, Issue 4, Page 665-678, October 2026.
ABSTRACT Background Gastrointestinal bleeding is very common among hemodialysis patients. This high bleeding risk is caused by uremic platelet dysfunction, vascular fragility, intradialytic hemodynamic instability, and widespread antithrombotic therapy.
Andreas Smyrlis, Konstantia Kantartzi, Konstantinos Mimidis, Stylianos Panagoutsos   +3 more
wiley   +1 more source

An Automated Microfluidic System for Haemostasis Assessment in Cirrhosis With Thrombocytopenia

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background & Aims Conventional laboratory tests do not capture platelet–vessel wall interactions (primary haemostasis) occurring in vivo, limiting guidance before invasive procedures. This is relevant in patients with thrombocytopenia, hallmark of advanced cirrhosis. Microfluidic assays may overcome these limitations.
Niccolò Bitto, Giulia Tosetti, Armando Tripodi, Anna Lecchi, Silvia La Marca, Lidia Padovan, Erica Scalambrino, Marigrazia Clerici, Camilla Caputo, Martina Lucà, Massimo Primignani, Anna Ludovica Fracanzani, Pietro Lampertico, Flora Peyvandi, Vincenzo La Mura   +14 more
wiley   +1 more source

Obesity‐Related Coagulation Activation in Adolescents and Children: A Systematic Review and Meta‐Analysis

Obesity Reviews, Volume 27, Issue 10, October 2026.
Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold, Hans‐Jonas Meyer, Manuel Florian Struck, Shrey Kohli, Akash Mathew, Gyulten Mangova, Alexey Surov, Matthias Blüher, Berend Isermann, Silke Zimmermann   +9 more
wiley   +1 more source