Results 11 to 20 of about 20,849 (211)

Solar Vortex Tubes: Vortex Dynamics in the Solar Atmosphere [PDF]

open access: yesThe Astrophysical Journal, 2020
Abstract In this work, a state-of-the-art vortex detection method, Instantaneous Vorticity Deviation, is applied to locate three-dimensional vortex tube boundaries in numerical simulations of solar photospheric magnetoconvection performed by the MURaM code.
Suzana S. A. Silva   +4 more
openaire   +4 more sources

Vortex dynamics in anisotropic traps [PDF]

open access: yesPhysical Review A, 2010
We investigate the dynamics of linear vortex lattices in anisotropic traps in two-dimensions and show that the interplay between the rotation and the anisotropy leads to a rich but highly regular dynamics.
McEndoo, Suzanne, Busch, Thomas
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Dynamics of a Pinned Magnetic Vortex [PDF]

open access: yesPhysical Review Letters, 2006
We observe the dynamics of a single magnetic vortex pinned by a defect in a ferromagnetic film. At low excitation amplitudes, the vortex core gyrates about its equilibrium position with a frequency that is characteristic of a single pinning site. At high amplitudes, the frequency of gyration is determined by the magnetostatic energy of the entire ...
R L, Compton, P A, Crowell
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Dynamics of Polar Vortex Crystallization

open access: yesPhysical Review Letters
3 ...
S. Rijal   +3 more
openaire   +3 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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