Results 21 to 30 of about 3,027,157 (239)
An experimental study is conducted to analyze a streamwise-oriented vortex and investigate the unsteady interaction with a finite-aspect-ratio wing. A pressurized vortex tube is used to generate streamwise vortices in a wind tunnel and the resulting flow
Bailey Carlson +2 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Vortex/inflectional-wave interactions with weakly three-dimensional input [PDF]
The subtle impact of the spanwise scaling in nonlinear interactions between oblique instability waves and the induced longitudinal vortex field is considered theoretically for the case of a Rayleigh-unstable boundary-layer flow, at large Reynolds numbers.
Timoshin, SN, Smith, FT
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
This file unit contains the first volume of The Vortex, a student led publication established on the University of Central Arkansas campus in ...
The Vortex Magazine of Literature and Fine Arts; University of Central Arkansas Department of English
core +1 more source
Chirality selection in the vortex state of magnetic nanodisks with a screw dislocation
Structural defects in magnetic crystalline materials may locally change magnetic properties and can significantly influence the behavior of magnetic nanostructures.
Rößler U. K., Butenko A. B.
doaj +1 more source
Wingtip Vortex Alleviation Using a Reverse Delta Type Add-on Device
The result of interactions of a wingtip vortex of a half-span wing and vortices generated by a slender reverse delta type add-on device were studied using Particle Image Velocimetry in a closed-loop low-speed wind tunnel.
Afaq Altaf
doaj +1 more source

