Results 61 to 70 of about 10,967 (294)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
In uncertainty we trust: a median voter model with risk aversion [PDF]
Financial Theory and Practice, 2011 The principal-agent problem and uncertainty are some of the key factors affecting financial and political markets. Fear of the unknown plays an important role in human decision making, including voting.
Pavel A. Yakovlev
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Reducibility of higher-order to pairwise interactions: Social impact models on hypergraphs
Physical Review ResearchWe show that a general class of node-update social impact models with higher-order interactions on hypergraphs can be exactly mapped to an equivalent model with pairwise interactions on a weighted projected network. This mapping preserves the microscopic
Jaume Llabrés +3 more
doaj +1 more source
The noisy veto-voter model: a recursive distributional equation on [0, 1] [PDF]
, 2008 We study a particular example of a recursive distributional equation (RDE) on the unit interval. We identify all invariant distributions, the corresponding `basins of attraction', and address the issue of endogeny for the associated tree-indexed problem,
Sheehan, Marcus, Jacka, Saul D.
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Time scales in the dynamics of political opinions and the voter model
New Journal of PhysicsOpinions in human societies are measured by political polls on time scales of months to years. Such opinion polls do not resolve the effects of individual interactions but constitute a stochastic process. Voter models with zealots (individuals who do not
Philipp G Meyer, Ralf Metzler
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
SAGE Open, 2015 Proponents of voter photographic identification (ID) laws in the United States have argued that such measures can increase overall voter turnout. The implications of this proposition contradict classic models of voting behavior, which state that voting ...
Russell Weaver
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source