Results 51 to 60 of about 36,279 (314)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Participation of Citizens of the Republic of Kalmykia in the Implemention of the Federal Law on Elections of the President of the Russian Federation

Oriental Studies, 2018
The article deals with the issues of formation and development of federal law on elections of the President of the Russian Federation, democratization of the electoral law and procedure in the 1990-s.
G. Maksimov
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Description of Banjar Ethnic Voter Behavior: Lessons from the Simultaneous Regional Head Elections for the Governor and Vice Governor of Central Kalimantan Province in 2020

Society, 2022
This study was motivated by the low voter turnout in the 2020 Regional Head Election for Governor and Vice Governor in Central Kalimantan Province, Indonesia.
Ricky Zulfauzan, Charles Hutapea, Nur Elysa Mitharie   +2 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The Dynamics of Regional Head Elections in the Digital Era in Indonesia: The Perspective of First-Time Voters

Journal of Legal Studies
Indonesia’s Regional Head Elections in 2024 show significant changes in political campaign strategies, especially with the increasing use of social media as the main tool.
Mulyadi Dedi, Putri Kayla Andini, Aulia Salsabila Hadi, Akbar Rivaldi Aka, Mawardi Muhamad Fahri, Garnita Camiliya Fakhriyah   +5 more
doaj   +1 more source

Issues in Political Campaigns during Nigeria's 2023 Presidential Election [PDF]

Social Sciences and Education Research Review
This conceptual study is a focus on the issues that were given prominence during the campaigns run-up to the 2023 presidential election conducted in Nigeria.
Kelvin INOBEMHE, Wisdom Iheanyichukwu OKEZIE, Nick-Tansi Saint UDEH, Suleiman GARBA, Oluwatobi Enitan MODEYIN, Momoh USMAN   +5 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Voting Behavior of Voters in Banica, Roxas City

JPAIR, 2009
This descriptive-correlational study determined the voting behavior of voters in Banica, Roxas City. The respondents were 246 randomly selected registered voters taken from 18 polling precincts using the stratified proportional sampling.
Randy R. Gigawin
doaj   +1 more source