Results 31 to 40 of about 130,737 (314)

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser   +6 more
wiley   +1 more source

Vote Early, Vote Often [PDF]

open access: yesQueue, 2004
I usually shun clichés like the plague, but could not resist this oft-quoted slogan that sums up what I like to call Psephological Cynicism. Psephology is the huge and growing branch of mathematics (with frequent distractions from sociologists, psychologists, political scientists, and allied layabouts) that studies the structure and effectiveness of ...
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Why Not a Philosopher King? and Other Objections to Epistocracy

open access: yesPhenomenology and Mind, 2019
In this paper I will examine epistocracy as a form of limiting the political agency of some citizens (by removing their political rights) and offer an internal critique of it.
Dragan Kuljanin
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Towards a Global History of Voting: Sovereignty, the Diffusion of Ideas, and the Enchanted Individual

open access: yesReligions, 2012
This article suggests a framework for moving toward a global history of voting and democracy that focuses less on the diffusion of European ideas (however important those ideas were) than on embedding the history of voting within a worldwide history of ...
David Gilmartin
doaj   +1 more source

Optimal Policymaking under Yardstick Vote: An Experimental Study

open access: yesGames, 2022
We develop a numerical model that simulates the evolution of a virtual population with an incentive and ability-based wage, capital yield from savings, social welfare system, and total income subject to taxation and political turnovers.
Albert Argilaga, Jijian Fan
doaj   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

An Adaptive Ensemble Machine Learning Model for Intrusion Detection

open access: yesIEEE Access, 2019
In recent years, advanced threat attacks are increasing, but the traditional network intrusion detection system based on feature filtering has some drawbacks which make it difficult to find new attacks in time.
Xianwei Gao   +4 more
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo   +19 more
wiley   +1 more source

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