Results 71 to 80 of about 1,665 (152)
Journal of Neuroendocrinology, Volume 37, Issue 3, March 2025.The thera(g)nostic approach with somatostatin analog‐based agents extends beyond gastroenteropancreatic neuroendocrine tumors. Understanding tumor biological mechanisms is essential for optimizing treatment strategies. Abstract First isolated by Brazeau et al. in 1972, somatostatin (SST) is a neuropeptide known for regulating various signaling pathways
Giulia Santo +3 more
wiley +1 more source
International Journal of Genomics, Volume 2025, Issue 1, 2025.This study investigates the promoter region and regulatory elements of chicken insulin‐like growth factor (IGF) and vasoactive intestinal polypeptide (VIP) genes associated with reproductive traits. Several in silico tools, such as Neural Network Promoter Prediction (NNPP), Multiple Expectation maximizations for Motif Elicitation (MEME‐Suite), GC ...
Bosenu Abera +4 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2020 Cognitive impairment is one of the major symptoms in most neurodegenerative disorders such as Alzheimer’s (AD), Parkinson (PD), and Huntington diseases (HD), affecting millions of people worldwide.
Irene Solés-Tarrés +3 more
doaj +1 more source
GABAergic signalling in the suprachiasmatic nucleus is required for coherent circadian rhythmicity
European Journal of Neuroscience, Volume 60, Issue 11, Page 6652-6667, December 2024.Genetic disruption of GABAergic synaptic transmission by deletion of the vesicular GABA transporter within the suprachiasmatic nucleus of adult mice results in the eventual deterioration of physiological and behavioural rhythmicity in vivo and concomitant neuronal desynchrony in vitro.
Nathan Klett +9 more
wiley +1 more source
Neuropeptide Receptors: Novel Targets for HIV/AIDS Therapeutics
Pharmaceuticals, 2011 The vasoactive intestinal peptide/pituitary adenylyl cyclase-activating polypepetide (VPAC) receptors are important for many physiologic functions, including glucose homeostasis, neuroprotection, memory, gut function, modulation of the immune system and ...
Donald R. Branch
doaj +1 more source
Journal of Neurochemistry, Volume 168, Issue 9, Page 3250-3267, September 2024.Pituitary adenylate cyclase‐activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are neuroprotective peptides. Their beneficial activities occur via three G protein‐coupled receptors, PAC1, VPAC1 and VPAC2. We found that PAC1 receptor activation contributes to most of the beneficial activities of the neuropeptides in an experimental ...
Margo I. Jansen +5 more
wiley +1 more source
Expression des Vasoaktiven Intestinalen Polypeptid-Rezeptors VPAC2 beim Bullösen Pemphigoid
, 2008 Mast cells and neuropeptides are important components of the neuroimmunocutane system. VPAC2, a neuropeptide-receptor for vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP), is expressed abundantly in the central nervous system and peripheral tissues and mediates a multitude of biological functions.
openaire +2 more sources
British Journal of Pharmacology, Volume 181, Issue 15, Page 2655-2675, August 2024.Background and Purpose The spinal cord is a key structure involved in the transmission and modulation of pain. Pituitary adenylate cyclase‐activating peptide (PACAP) and vasoactive intestinal peptide (VIP), are expressed in the spinal cord. These peptides activate G protein‐coupled receptors (PAC1, VPAC1 and VPAC2) that could provide targets for the ...
Zoe Tasma +9 more
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2019 Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) is an endogenous neuropeptide with distinct functions including the regulation of inflammatory processes.
Caio Andreeta Figueiredo +9 more
doaj +1 more source
, 2005 Prepro-vasoactive intestinal peptide (VIP) mRNA codes for two neuropeptides: VIP and peptide histidine isoleucine (PHI). Two VIP receptors, shared with a similar affinity by pituitary adenylate cyclase-activating polypeptide (PACAP), have been cloned: VPAC(1) and VPAC(2). PHI binds to these receptors with a lower affinity.
Rangon, Claire-Marie +9 more
openaire +1 more source