Results 181 to 190 of about 112,338 (245)

Individualized Atrophy‐Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed‐Effects Modeling

Annals of Neurology, EarlyView.
Objective Age of symptom onset is highly variable in familial frontotemporal lobar degeneration (f‐FTLD). Accurate prediction of onset would inform clinical management and trial enrollment. Prior studies indicate that individualized maps of brain atrophy can predict conversion to dementia in f‐FTLD.
Shubir Dutt, Dana Leichter, Yann Cobigo, Amy Wolf, John Kornak, Annie Clark, Lucy L. Russell, Arabella Bouzigues, David M. Cash, Martina Bocchetta, Molly Olzinski, Brian Appleby, Ece Bayram, Barbara Borroni, Andrea Bozoki, Chris R. Butler, David Clark, Rhian S. Convery, R. Ryan Darby, Alexandre de Mendonça, Bradford Dickerson, Kimiko Domoto‐Reilly, Simon Ducharme, Eve Ferry‐Bolder, Elizabeth Finger, Phoebe H. Foster, Douglas R. Galasko, Daniela Galimberti, Alexander Gerhard, Nupur Ghoshal, Caroline Graff, Neill Graff‐Radford, Ian M. Grant, Chadwick M. Hales, Lawrence S. Honig, Ging‐Yuek Hsiung, Edward D. Huey, David Irwin, Lize C. Jiskoot, Walter Kremers, Justin Y. Kwan, Robert Laforce, Isabelle Le Ber, Gabriel C. Léger, Johannes Levin, Irene Litvan, Ian R. Mackenzie, Mario Masellis, Mario F. Mendez, Fermin Moreno, Chiadi Onyike, Markus Otto, Belen Pascual, Peter Pressman, Rosa Rademakers, Eliana Marisa Ramos, Aaron Ritter, Erik D. Roberson, James B. Rowe, Raquel Sanchez‐Valle, Isabel Santana, Harro Seelaar, Allison Snyder, Sandro Sorbi, Matthis Synofzik, Maria Carmela Tartaglia, Pietro Tiraboschi, John C. van Swieten, Marijne Vandebergh, Rik Vandenberghe, Hilary W. Heuer, Bruce L. Miller, William W. Seeley, Maria Luisa Gorno‐Tempini, Joel H. Kramer, Leah Forsberg, Kejal Kantarci, Bradley F. Boeve, Adam L. Boxer, Jonathan D. Rohrer, Howard J. Rosen, Adam M. Staffaroni, FTD Prevention Initiative (FPI) investigators   +82 more
wiley   +1 more source

Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?

Annals of Neurology, EarlyView.
Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano, Francesca Palumbo, Gabriele Mora, Salvatore Gallone, Giovanni De Marco, Ilaria Merulla, Claudia Paolantonio, Alessandra Maccabeo, Antonio Canosa, Umberto Manera, Rosario Vasta, Barbara Iazzolino, Marcella Testa, Giuseppe Fuda, Paolina Salamone, Giulia Marchese, Federico Casale, Cristina Moglia, Andrea Calvo, Giuseppe Borghero, Adriano Chiò   +20 more
wiley   +1 more source

Two‐Nanosensor Electrochemical Profiling of Catecholamine Vesicle Interactions With Acute and Chronic Stress Granules in Living Cells

Angewandte Chemie, EarlyView.
A two‐nanosensor electrochemical strategy quantitatively distinguishes reactive oxygen species (ROS) in stress granules (SGs) from catecholamines in vesicles inside living cells. Chronic SGs formed under prolonged stress show elevated ROS and slower release, consistent with SG aging, and promote neurotransmitter loading likely through vesicle fusion ...
Hui Gu, Chaoyi Gu, Andre Du Toit, Andrew G. Ewing   +3 more
wiley   +2 more sources

Examination of the effects of virtual reality glasses and stress ball applications on pain, vital signs, anxiety, fear, satisfaction, and comfort levels during the dressing changes in patients who underwent abdominal surgery. [PDF]

Turk J Surg
Yanık Z, Baksi A.
europepmc   +1 more source

Induced Photoelectron Circular Dichroism as a Probe for Distinguishing Diastereotopic Lone Electron Pairs

Angewandte Chemie, EarlyView.
Gas‐phase complexation of chiral methyloxirane by achiral phenol results in induced chiroptical response of phenol. Two pseudo enantiomer complexes are observed, corresponding to hydrogen bonding from phenol to either of the lone electron pair of the methyloxirane oxygen, denoted as Pro R and Pro S, with opposite chiral deformation of phenol and ...
Etienne Rouquet, Valéria Lepère, Gustavo A. Garcia, Laurent Nahon, Rodolphe Vuilleumier, Anne Zehnacker   +5 more
wiley   +2 more sources

SomaVR: A low-cost virtual reality platform and implementation framework for medical education in resource-limited settings. [PDF]

PLOS Digit Health
Nsubuga M, Kebirungi G, Please H, Buyego P, Mutegeki H, Kimera R, Dhanda J, Cruz P, McCarthy M, Hurt D, Giovanni MY, Whalen C, Tartakovsky M, Jjingo D.   +13 more
europepmc   +1 more source

Der Nicht‐Adiabatische Charakter von Substituenteneffekten in Azobenzol

Angewandte Chemie, EarlyView.
Vereinheitlichung Nicht‐Adiabatischen Schaltens: die thermische Z→E Isomerisierung von para‐substitutierten Azobenzolen verläuft über einen einzelnen Reaktionsweg mit nicht‐adiabatischem Charakter. Anstatt eines mechanistischen Wechsels spiegelt der bekannte V‐förmige Hammett Graph ein Artefakt des σp Parameters, zeigt so die Grenzen von DFT auf und ...
Jacob Jan van der Wal, Roman Yu. Peshkov, Jorn D. Steen, Nadja A. Simeth, Stefano Crespi   +4 more
wiley   +1 more source

Co-Designing a Virtual Reality Intervention for Adolescents With Psychosis. [PDF]

Early Interv Psychiatry
Holgersen G, Barsnes A, Pedersen OB, Nordgreen T, Elgen IB.   +4 more
europepmc   +1 more source

The two sides of VR utopia

NECSUS
Da Ye Kim
doaj   +1 more source

Effectiveness of Virtual Reality-Based Early Rehabilitation Strategies on Pain, Sleep, Anxiety, Balance, Cognition, and Limb Motor Function in Adult Intensive Care Unit Patients: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

J Med Internet Res
Wu F, Wu Y, Xing Y, Cai W, Zhang R.
europepmc   +1 more source