Results 211 to 220 of about 207,959 (296)

Liquid Jetting‐Based Miniature Robotic Navigation in Confined Fluidic Spaces

open access: yesAdvanced Intelligent Systems, EarlyView.
We introduce a new class of liquid‐jetting‐based miniature robots (JetBots) ranging in size from mm‐to‐cm, featuring a unified approach in design, fabrication, and actuation. They demonstrate fast locomotion (30.3 cm/s), rapid steering (648.8°/s), and diverse functions, such as puncturing soft materials and unlimited cargo sampling and delivery, paving
Debasish Roy, Tianlu Wang
wiley   +1 more source

SiOx‐Based Probabilistic Bits Enabling Invertible Logic Gate for Cryptographic Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
To enable lightweight hardware encryption and decryption, a Ti/SiOx/Ti threshold switching device is engineered to generate controllable stochastic oscillations. By tuning the input voltage, the device produces a programmable spike probability governed by intrinsic switching dynamics, enabling probabilistic bits that construct an invertible ...
Jihyun Kim, Hyeonsik Choi, Jiyong Woo
wiley   +1 more source

Multimodal Psychophysiological Assessment of Craving in Patients With Alcohol Dependence During Virtual Reality Cue Exposure: Exploratory Single-Arm Clinical Study. [PDF]

open access: yesJMIR Serious Games
Lütt A   +15 more
europepmc   +1 more source

The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta‐Analysis of the European Myeloma Network (EMN)

open access: yesAmerican Journal of Hematology, EarlyView.
Our meta‐analysis showed significant improvement of PFS with lenalidomide, proteasome inhibitors, and CD38‐based therapies. A significant OS benefit was noted only with lenalidomide in transplant‐eligible (TE) patients, while CD38‐directed therapy showed a trend toward improved OS.
Heinz Ludwig   +25 more
wiley   +1 more source

Dordaviprone Maintenance After Allogeneic HCT for High‐Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Dordaviprone is a first‐in‐class small‐molecule imipridone. In preclinical studies, it is active against leukemia cells harboring a TP53 mutation or complex karyotype and leukemia stem cells while sparing normal bone marrow cells. This study aimed to determine the safety of dordaviprone maintenance after allogeneic hematopoietic cell ...
Vijaya Raj Bhatt   +8 more
wiley   +1 more source

Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman   +15 more
wiley   +1 more source

Developmental and Phenotypic Outcomes in Mild Phenylalanine Hydroxylase Deficiency

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Benign hyperphenylalaninemia (bHPA) is defined as elevated phenylalanine (Phe) levels remaining ≤ 360 μmol/L (6 mg/dL) and not requiring medical intervention. Individuals with bHPA may demonstrate a rise in their Phe levels > 360 μmol/L, effectively developing a mild PKU phenotype requiring therapy to prevent neurocognitive complications. This
Aaron Williams   +8 more
wiley   +1 more source

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