Results 121 to 130 of about 16,913 (176)
Numerical Aspects of Turbulent Blood Flow in Aorta: A Systematic Review
The aim of this systematic review is to systematize the methodological approaches used in the state‐of‐the‐art literature, including the choice of turbulence models, validation methods, as well as the identification of the main hemodynamic parameters characterizing turbulent flow.
Nikita Skripka, Alex G. Kuchumov
wiley +1 more source
A side-sensitive synthetic chart combined with a VSS chart
A. Costa, M. Machado
semanticscholar +1 more source
Circular system converting wastewater sludge (WWS) into PHA bioplastics via acidification and MMC biosynthesis. System highlights LCA framework, showing GWP trade‐offs against fossil plastics and costs of $3–5/kg PHA, ultimately achieving lower carbon footprints and resource recovery for a sustainable bioeconomy.
Anwar Ahmad +9 more
wiley +1 more source
Abstract Sasanlimab is a monoclonal antibody (mAb) which blocks human programed cell death protein 1. It is administered subcutaneously (SC), currently under development for non‐muscle invasive bladder cancer (NMIBC) with a recommended flat dose of 300 mg every 4 weeks (Q4W).
Joanna C. Masters +8 more
wiley +1 more source
Full‐thickness skin defects remain a major reconstructive challenge. This randomized trial demonstrates that single‐stage composite grafting using intraoperatively prepared autologous EpiSC‐enriched suspensions is feasible. EpiSC augmentation improves complete wound healing and yields superior 6‐month scar outcomes compared with standard grafting ...
Zhicheng Hu +16 more
wiley +1 more source
ABSTRACT This study quantified age‐related differences in fluoxetine pharmacokinetics and evaluated the influence of CYP2D6 phenotype using physiologically based pharmacokinetic (PBPK) modeling integrated with clinical therapeutic drug monitoring data.
Yoo Jin Jang +2 more
wiley +1 more source
ABSTRACT Accurate physiologically based pharmacokinetic (PBPK) simulation of drug–drug interaction (DDI) potential requires estimation of the relative contribution of the impacted pathway. While fraction metabolized by CYP enzymes is usually estimated using dedicated clinical DDI studies with strong CYP inhibitors, this approach might not be available ...
Ian E. Templeton +6 more
wiley +1 more source
Compact VSS and Efficient Homomorphic UC Commitments
I. Damgård +3 more
semanticscholar +1 more source
ABSTRACT Brensocatib, a competitive and reversible oral DPP1 inhibitor, at 10 and 25 mg significantly reduced pulmonary exacerbation burden, and 25 mg also reduced lung function decline vs. placebo in patients with non‐cystic fibrosis bronchiectasis, hereafter bronchiectasis, in ASPEN (NCT04594369).
Helen Usansky +8 more
wiley +1 more source

