Results 141 to 150 of about 1,849,598 (165)

Trans Hammerhead Ribozyme: Ligation vs. Cleavage [PDF]

, 2007
Trans hammerhead ribozymes are considered from the point of view of the RNA world theory. An attempt was made to reconstruct the ‘ancestors’ of contemporary hammerhead ribozymes with improved ligation activity by altering the sequence of trans hammerhead motifs.
Valentin V. Vlassov, Alya G. Venyaminova, A.S. Privalova, M. A. Vorobjeva   +3 more
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The solution structure of the VS ribozyme active site loop reveals a dynamic "hot-spot".

Journal of Molecular Biology, 2004
The VS ribozyme is the largest ribozyme in its class and is also the least structurally characterized thus far. The current working model of the VS ribozyme locates the active site in stem-loop VI. The solution structure of this active site loop was determined using high resolution NMR spectroscopy.
J. Flinders, T. Dieckmann
semanticscholar   +4 more sources

Reaction conditions and kinetics of self-cleavage of a ribozyme derived from Neurospora VS RNA

Biochemistry, 1993
We have investigated the self-cleavage reaction performed by a ribozyme that contains 164 nucleotides of Neurospora VS RNA. Self-cleavage requires a divalent cation, magnesium being more effective than manganese or calcium. Spermidine or monovalent cations stimulate the reaction but cannot replace magnesium.
Joan E. Olive, Richard A. Collins
openaire   +2 more sources

Faculty Opinions recommendation of The global structure of the VS ribozyme.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2002
Thorsten Dieckmann
openalex   +2 more sources

Faculty Opinions recommendation of The A730 loop is an important component of the active site of the VS ribozyme.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2001
Thorsten Dieckmann
openalex   +2 more sources

Kinetic studies of the Neurospora VS ribozyme

Collection Symposium Series, 2002
Iain A. Murray, Svetomir B. Tzokov, Yana S. Kovacheva, Jane A. Grasby   +3 more
openaire   +2 more sources

Crystal structure of the VS ribozyme - wild-type C634

, 2017
Saurja DasGupta, N. Suslov, J. Piccirilli   +2 more
semanticscholar   +1 more source

Crystal Structure of the VS ribozyme-A756G mutant

, 2015
J. Piccirilli, N. Suslov, Saurja DasGupta, H. Huang, D. Lilley, P. Rice   +5 more
semanticscholar   +1 more source

Crystal structure of the VS ribozyme - G638A mutant

, 2015
J. Piccirilli, N. Suslov, Saurja DasGupta, H. Huang, D. Lilley, P. Rice   +5 more
semanticscholar   +1 more source

NMR structure of the II-III-VI three-way junction from the VS ribozyme and identification of magnesium-binding sites using paramagnetic relaxation enhancement

, 2014
É. Bonneau, Nicolas Girard, S. Lemieux, P. Legault   +3 more
semanticscholar   +1 more source