The frequency and severity of congenital heart disease vary extensively in individuals with 22q11.22–23 distal deletions. Reduced gene dosage particularly within the low copy repeat (LCR22) D–E region including MAPK1 and HIC2 conveys risk for these defects.
Tanner J. Nelson +22 more
wiley +1 more source
Atrioventricular Conduction Disturbance After Perimembranous Ventricular Septal Defect Closure. [PDF]
Kwok GHT, Wong CK, Chen HR, Un KC.
europepmc +1 more source
ABSTRACT Background Adults with Down syndrome (DS) are less physically active than those without DS. Among adults with DS, those with congenital heart disease (CHD) have lower physical activity than those without CHD. Many trials exclude people with CHD from exercise trials; thus, the safety and effectiveness of these interventions for increasing ...
Julianne G. Clina +10 more
wiley +1 more source
Timing of Intervention and Long-Term Outcomes in Mild Congenital Heart Disease: A 35-Year Study From the Pediatric Cardiac Care Consortium. [PDF]
Perlow GL +6 more
europepmc +1 more source
Optical Mapping of Pacing‐Elicited Slow Waves in the Swine Stomach: Role of Virtual Electrodes
Unipolar electrical pacing stimuli delivered to the stomach wall induce adjacent regions of both depolarized and hyperpolarized tissue known as virtual electrodes. Electrical slow waves elicited by pacing start from depolarized virtual electrodes approximately 1 cm from the pacing electrode site and not from the electrode site itself.
Hanyu Zhang +6 more
wiley +1 more source
A Modified External Fixation Device for Treating Open Fractures of the Lower Extremities: Two Case Reports. [PDF]
Liu S +5 more
europepmc +1 more source
Abstract Introduction Addition of silicate rock powder (SRP) is an increasingly used measure to restore vegetation and fauna on acidified mineral‐poor soils in protected areas. In theory, however, the positive effects of SRP addition on vegetation may be offset by grazing and browsing ungulates attracted to higher‐quality forage.
Moniek J. M. Heurman +6 more
wiley +1 more source
Vertical Right Axillary Thoracotomy for Repair of Ventricular Septal Defects in Infants and Children: Experience with 50 Consecutive Cases. [PDF]
Essa Y +5 more
europepmc +1 more source
Structure mirroring function: What's the ‘matter’ with the funny current?
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley +1 more source
Single-stage surgical modification for neonatal aortic coarctation and ventricular septal defect: a case report. [PDF]
Yang X, Xing P, Hou K, Chen R, Pan S.
europepmc +1 more source

