Results 181 to 190 of about 2,945,640 (398)

EPCO-12. IN VIVO PERTURB-SEQ DEFINES BIOLOGICAL DRIVERS AND THERAPEUTIC VULNERABILITIES UNDERLYING RADIOTHERAPY RESISTANCE IN GLIOBLASTOMA [PDF]

, 2023
John Liu, Joanna Pak, Christopher Zou, Sixuan Pan, Emily Payne, Kyla Foster, Katie Lin, Tim Casey-Clyde, Kyounghee Seo, Thomas O’Loughlin, David Wu, Daniel A. Lim, Harish N. Vasudevan, Aarón Díaz, Tomoko Ozawa, Mitchel S. Berger, John de Groot, William A. Weiss, Luke A. Gilbert, David R. Raleigh   +19 more
openalex   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

The engagement in the non-agricultural sector as a risk-mitigating strategy in rural Pakistan [PDF]

The paper investigates whether, as is often suggested by the literature, diversification towards the non-agricultural sector is considered as a risk-mitigating strategy by rural Pakistani households.
Tania Rajadel
core  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Costs and benefits of adapting to climate change at six meters below sea level [PDF]

Climate change increases the vulnerability of low-lying coastal areas. Careful spatial planning can reduce this vulnerability. An assessment framework aimed at reducing vulnerability to climate change enables decision-makers to make better informed ...
Bruin, K., de, Goosen, H., Groeneveld, R.A., Ierland, E.C., van   +3 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Corrigendum to “Climate change impacts and adaptations on health of Internally Displaced People (IDP): An exploratory study on coastal areas of Bangladesh” [Heliyon 6 (9) (September 2020) Article e05018]”

Heliyon, 2020
Md. Arif Chowdhury, Md. Khalid Hasan, Md. Robiul Hasan, Tahmina Bintay Younos   +3 more
doaj   +1 more source

Seismic response of mountain tunnel induced by fault slip

Scientific Reports
With the rapid development of Chinese transportation networks, such as the Sichuan-Tibet railway, numerous tunnels are under construction or planned in mountainous regions. Some of these tunnels must traverse or be situated near active fault zones, which
Chen Xia, Zian Wang, Yongsheng He, Yeqing Chen, Chunhai Li, Lei Shi, Chuan Zhao   +6 more
doaj   +1 more source

Targeting the Vulnerable and the Choice of Vulnerability Measures: Review and Application to Pakistan [PDF]

In this paper, the concept of vulnerability of the poor’s welfare and its practical measures are scrutinised in order to derive implications for targeting poverty reduction policies toward vulnerable households.
Takashi Kurosaki
core  

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source