Results 61 to 70 of about 345,903 (245)

Vulnerability Analysis of a Road Network for Liquid Chemicals Transportation Considering Intentional Attack

Applied Sciences
While tank vehicles are in the process of transporting liquid chemicals, the transportation task may be delayed or terminated due to disruptions in the transportation network.
Runfeng Cao, Feifeng Zheng
doaj   +1 more source

Analysis on Integrated Energy System Cascading Failures Considering Interaction of Coupled Heating and Power Networks

IEEE Access, 2019
As the coupling and integration of multi-energy flow in the integrated energy system (IES) deepen increasingly, the cascading failure will develop across different energy systems more easily and widely through the energy hub (EH).
Yi Pan, Fei Mei, Cheng Zhou, Tian Shi, Jianyong Zheng   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A Comprehensive Survey on Cognitive Cyber Security Analysis Using Machine Learning Approaches

IEEE Access
Cybersecurity threats have evolved in sophistication, necessitating the development of intelligent and adaptive defense mechanisms. Cognitive cybersecurity systems present the opportunity to provide answers to threat detection, vulnerability analysis ...
Waseem Khan, K. Ashoka, M. S. Abdul Razak, M. V. Manoj Kumar, R. Naseer   +4 more
doaj   +1 more source

Neutralizing BLE Beacon-Based Electronic Attendance System Using Signal Imitation Attack

IEEE Access, 2018
Many emerging location- or proximity-based applications use Bluetooth low energy (BLE) beacons thanks to the increasing popularity of the technology in mobile systems.
Moonbeom Kim, Jongho Lee, Jeongyeup Paek
doaj   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Research on Performance Optimization and Vulnerability Assessment of Tension Isolation Bearings for Bridges in Near-Fault Zones: A State-of-the-Art Review

Buildings
This review offers a comprehensive analysis of the mechanical behavior and evolving design strategies of bridge bearings subjected to vertical seismic loading. Existing studies underscored that intense vertical ground motions—particularly those with high
Yuwen Wen, Ping Zhou, Yang Liu, Xiaojuan Ning, Houzheng Xia, Wenjun An, Chee-Loong Chin, Chau-Khun Ma   +7 more
doaj   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source