Results 91 to 100 of about 118,924 (255)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

iDetect for vulnerability detection in internet of things operating systems using machine learning. [PDF]

Sci Rep, 2022
Al-Boghdady A, El-Ramly M, Wassif K.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

IoT Firmware Emulation and Its Security Application in Fuzzing: A Critical Revisit

Future Internet
As IoT devices with microcontroller (MCU)-based firmware become more common in our lives, memory corruption vulnerabilities in their firmware are increasingly targeted by adversaries.
Wei Zhou, Shandian Shen, Peng Liu
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Vulnerability Detection in Binary Code Based on Constraint Satisfiability Checking

Безопасность информационных технологий, 2010
This article presents the method for purposeful detection of vulnerabilities depending on input data of application. It also describes the model-based testing tool Avalanche which applies this method for detection of vulnerabilities in binary code.
A. V. Filonenko, I. K. Isaev, D. V. Sidorov, Y. M. Tumanov   +3 more
doaj  

SPCBIG-EC: A Robust Serial Hybrid Model for Smart Contract Vulnerability Detection. [PDF]

Sensors (Basel), 2022
Zhang L, Li Y, Jin T, Wang W, Jin Z, Zhao C, Cai Z, Chen H.   +7 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

A Coverage-Guided Fuzzing Method for Automatic Software Vulnerability Detection Using Reinforcement Learning-Enabled Multi-Level Input Mutation

IEEE Access
Fuzzing is a popular and effective software testing technique that automatically generates or modifies inputs to test the stability and vulnerabilities of a software system, which has been widely applied and improved by security researchers and experts ...
Van-Hau Pham, Do Thi Thu Hien, Nguyen Phuc Chuong, Pham Thanh Thai, Phan The Duy   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source