Results 51 to 60 of about 118,924 (255)

A Comparative Study of Machine and Deep Learning Approaches for Smart Contract Vulnerability Detection

Technologies
The increasing use of blockchain smart contracts has introduced new security challenges, as small coding errors can lead to major financial losses. While rule-based static analyzers remain the most common detection tools, their limited adaptability often
Mohammed Yaseen Alhayani, Wisam Hazim Gwad, Shahab Wahhab Kareem, Moustafa Fayad   +3 more
doaj   +1 more source

Improving Security of Web Servers in Critical IoT Systems through Self-Monitoring of Vulnerabilities

Sensors, 2022
IoT (Internet of Things) systems are complex ones that may comprise large numbers of sensing and actuating devices; and servers that store data and further configure the operation of such devices.
Linxuan Song, Marisol García-Valls
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Deep Learning-Based Vulnerability Detection Solutions in Smart Contracts: A Comparative and Meta-Analysis of Existing Approaches

IEEE Access
In the short history of smart contracts, substantial losses have occurred due to unaccounted vulnerabilities in the smart contracts loaded onto the blockchain.
Michael Bresil, Pwc Prasad, Md Shohel Sayeed, Umar Ali Bukar   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Intracoronary Imaging in the Detection of Vulnerable Plaques [PDF]

Current Cardiology Reports, 2016
Coronary artery disease is the result of atherosclerotic changes to the coronary arterial wall, comprising endothelial dysfunction, vascular inflammation and deposition of lipid-rich macrophage foam cells. Certain high-risk atherosclerotic plaques are vulnerable to disruption, leading to rupture, thrombosis and the clinical sequelae of acute coronary ...
Batty, Jonathan A., Subba, Shristy, Luke, Peter, Gigi, Li Wing Chi, Sinclair, Hannah, Kunadian, Vijay   +5 more
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Inferring Patterns for Taint-Style Vulnerabilities With Security Patches

IEEE Access, 2019
Taint-style vulnerabilities can damage the service provided by mobile seriously. The pattern-based method is a practical way to detect taint-style vulnerabilities.
Tingyu Song, Xiaohong Li, Zhiyong Feng, Guangquan Xu   +3 more
doaj   +1 more source