Results 21 to 30 of about 559,628 (214)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
National legal system in relation to vulnerable population groups [PDF]
Stanovništvo, 2015 Vulnerable social groups can be recognized in everyday life, and local legal regulations identify them as well. Strategies and laws clearly identify the increased needs of vulnerable groups.
Sjeničić Marta
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
CURRENT COORDINATES OF ROMANIAN VULNERABLE GROUPS IN THE EUROPEAN CONTEXT [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014 Often, in European Union and Romanian legal documents or in research reports, the term ‘vulnerable group’ is used similarly to disadvantaged, marginalized, excluded or risk group; all these concepts are related to the broader phenomenon of poverty ...
MARIANA BĂLAN +2 more
doaj
Inclusion of vulnerable groups in health policies: Regional policies on health priorities in Africa
African Journal of Disability, 2013 Background: If access to equitable health care is to be achieved for all, policy documents must mention and address in some detail different needs of groups vulnerable to not accessing such health care.
Margie Schneider +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
EDUCAÇÃO EM DIREITOS HUMANOS COMO INSTRUMENTO DE TRANSFORMAÇÃO SOCIAL
LexCult, 2018 The World Conference on Human Rights considered that human rights education, training and public information are indispensable for establishing and promoting stable and harmonious relationships between communities and ...
Fernanda Baldanza, Reis Friede
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Neurodidactic teacher training program for educational dropouts in vulnerable groups
Frontiers in Education, 2023 Neurodidactic is presented as an effective teaching tool for creating an equitable society, regardless of the population. This educational methodology, which has recently been introduced in teacher training, supports students with functional diversity ...
Claudia De Barros Camargo +3 more
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source