Results 201 to 210 of about 434,617 (300)

Shifting emergency department utilization patterns among vulnerable populations during the COVID-19 pandemic. [PDF]

BMC Public Health
McCormack L, Chinthala LK, Elias E, Madlock-Brown C.   +3 more
europepmc   +1 more source

Vulnerable Populations in the Long Term Care Continuum

, 2004
Katz, Paul R., Mezey, Mathy D., and Kapp, Marshall B.   +2 more
core  

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Addressing Infectious Diseases in Vulnerable Populations Under the Auspices of One Health: A Call for Action in Europe. [PDF]

Infect Dis Rep
Lakatos B, Farkas FB, Guido G, Saracino A, Di Gennaro F.   +4 more
europepmc   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Recruitment Strategies to Prevent Fraudulent Virtual Enrollment While Respecting Privacy in Vulnerable Populations. [PDF]

Qual Health Res
Burwell N, Mbakop LC, Branch K, Lowenthal ED, Clark RRS, Nightingale KJ.   +5 more
europepmc   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Heatwaves, Cold Spells, and Renal Disease Mortality in Japan: Vulnerable Populations and Temporal Trends (1979-2019). [PDF]

Environ Health (Wash)
Htay ZW, Ng CFS, Kim Y, Lim YH, Iwagami M, Hashizume M.   +5 more
europepmc   +1 more source

Monitoring the Impact of the Medicare Fee Schedule on Access to Care for Vulnerable Populations

, 1997
Colby, David C., Trude, Sally
core  

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source