Results 101 to 110 of about 230,949 (287)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

AN OVERVIEW OF ROAD SAFETY IN LEBANON [PDF]

open access: yes, 2013
Road traffic injuries are a growing public health and development problem. According to the World Health Organization (WHO), 1.2 million people are killed in road traffic crashes around the world each year.
M. Choueiri, Bernard   +2 more
core  

Towards Secure and Safe Appified Automated Vehicles

open access: yes, 2017
The advancement in Autonomous Vehicles (AVs) has created an enormous market for the development of self-driving functionalities,raising the question of how it will transform the traditional vehicle development process. One adventurous proposal is to open
Chen, Qi Alfred   +3 more
core   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney   +3 more
wiley   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou   +10 more
wiley   +1 more source

Road Safety Analysis of Urban Roads: Case Study of an Italian Municipality

open access: yesSafety, 2018
Attention to the most vulnerable road users has grown rapidly over recent decades. The experience gained reveals an important number of fatalities due to accidents in urban branch roads.
Francesca Demasi   +2 more
doaj   +1 more source

Exploring Determinants of Urban Motorcycle Accident Severity: The Case of Barcelona [PDF]

open access: yes
Public authorities and road users alike are increasingly concerned by recent trends in road safety outcomes in Barcelona, which is the European city with the highest number of registered Powered Two-Wheel (PTW) vehicles per inhabitant,.
Daniel Albalate   +1 more
core  

Spatial variations in road collision propensities in London [PDF]

open access: yes, 2005
Propensity to be involved in a road traffic collision in Greater London is likely to depend on many factors, including personal mobility, lifestyle, behaviour, neighbourhood characteristics and environment.
Anderson, T.
core  

Review of Thin Lithium Metal Battery Anode Fabrication – Microstructure – Electrochemistry Relations

open access: yesAdvanced Materials, EarlyView.
Thin, lightweight lithium‐metal anodes are pivotal for practical high‐energy batteries. This review surveys processing routes that convert diverse Li precursors, e.g., ingots, melts, solutions, and vapor, into Li‐rich foils with controlled thickness, areal density, and tailored functionality.
Yuhang Hu   +6 more
wiley   +1 more source

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