Are train horns improving road safety? Road users’ perspective [PDF]
Train horns are used as a control at railway level crossing for safety. Despite their wide use, limited information exists on their actual safety benefits.
Watling, Christopher N. +5 more
core +1 more source
Basic principles of investigation and appointment of measures to improve road safety in places / areas of concentration of traffic accidents on motor roads [PDF]
Introduction. The increase in accidents on highways leads to the emergence of places and areas of concentration of traffic accidents, which, in turn, require a detailed examination to identify possible causes of accidents, determine ways to eliminate the
Oleksandr Pyna +2 more
doaj +1 more source
Integrating policy approaches for vulnerable road users [PDF]
In road safety circles, pedestrians, pedal cyclists and motorcyclists are often referred to as 'vulnerable road users' because of the high severity of injury that often occurs in impacts between these groups and cars.
Haworth, Narelle L.
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
What factors impact pedestrian and cyclist fatalities? A state level analysis
Background Pedestrian and bicyclist injuries and fatalities have increased since 2010 after a long downward trend. Trucks and SUVs, collectively called light trucks, have also increased in sales and size, which may affect pedestrians and bicyclists ...
Zoabe Hafeez, Malvi Mehta
doaj +1 more source
A Review of Trajectory Prediction Methods for the Vulnerable Road User
Predicting the trajectory of other road users, especially vulnerable road users (VRUs), is an important aspect of safety and planning efficiency for autonomous vehicles. With recent advances in Deep-Learning-based approaches in this field, physics- and classical Machine-Learning-based methods cannot exhibit competitive results compared to the former ...
Erik Schütz, Fabian B. Flohr
openaire +2 more sources
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Road traffic mortality in Zunyi city, China: A 10 – year data analysis (2013–2022)
Purpose: The study aimed to examine the pattern of motorization and the mortality rate related to road traffic crashes in Zunyi (a city in northern Guizhou province of China) from 2013 to 2022, and to identify the epidemiological characteristics of these
Tian-Jing Sun +5 more
doaj +1 more source
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
The multifaceted roles of lysosomes in cancer
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source

