Results 31 to 40 of about 7,922 (281)

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Biomimetic Iridescent Skin: Robust Prototissues Spontaneously Assembled from Photonic Protocells

open access: yesAdvanced Functional Materials, EarlyView.
Uniform nanoparticles are induced to form arrays (photonic crystals) in the cores of biopolymer capsules, endowing these ‘protocells’ with structural color. These protocells are then assembled into large self‐standing objects, i.e., prototissues, with robust mechanical properties as well as iridescent optical properties.
Medha Rath   +6 more
wiley   +1 more source

Too Sanitary for Vultures [PDF]

open access: yesScience, 2009
Letter.
Donázar, José A.   +3 more
openaire   +3 more sources

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

A Termite‐Inspired Alternative to Cement

open access: yesAdvanced Functional Materials, EarlyView.
A termite‐inspired composite of clay, cellulose, and lignin forms a dense fibrous network with concrete‐like strength (32 MPa) and superior elasticity, processed at ambient temperature. Abstract Clay combined with organic materials is used by termites as a strong and durable construction material for their mounds with minimal environmental impact. Here,
Oren Regev   +3 more
wiley   +1 more source

Egyptian Vulture in the Karatau Mountains and Adjacent Territories, Kazakhstan

open access: yesПернатые хищники и их охрана, 2022
Egyptian Vulture (Neophron percnopterus) is a globally threatened species. The northernmost limit of its breeding range is located in Kazakhstan and is fragmented into three large enclaves. The Karatau range is one such enclave. It was previously assumed
Igor V. Karyakin   +5 more
doaj   +1 more source

High‐Spatiotemporal‐Resolution Transparent Thermoelectric Temperature Sensor Arrays Reveal Temperature‐Dependent Windows for Reversible Photothermal Neuromodulation

open access: yesAdvanced Functional Materials, EarlyView.
Thermoelectric temperature sensors are developed that directly measure heat changes during optical‐based neural stimulation with millisecond precision. The sensors reveal the temperature windows for safe reversible neural modulation: 1.4–4.5 °C enables reversible neural inhibition, while temperatures above 6.1 °C cause permanent thermal damage.
Junhee Lee   +9 more
wiley   +1 more source

Predicting residents' intention to conserve the hooded vulture (Necrosyrtes monachus) in the Birem North District, Ghana

open access: yesHeliyon, 2020
The vulture as an important and specialized scavenger in human societies, helps clean the environment and prevents diseases. However, plummeting populations across the globe in the last three decades has led to the classification of some species as ...
Bright O. Kankam, Haruna Abukari
doaj   +1 more source

Preliminary analysis of double‐negative T, double‐positive T, and natural killer T‐like cells in B‐cell chronic lymphocytic leukemia

open access: yesCancer Medicine, 2023
Background B‐cell chronic lymphocytic leukemia (B‐CLL) is characterized by the expansion of CD5+ malignant B lymphocytes. Recent discoveries have shown that double‐negative T (DNT) cells, double‐positive T (DPT) cells, and natural killer T (NKT)‐cells ...
Luciana Valvano   +11 more
doaj   +1 more source

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