Results 31 to 40 of about 1,786 (140)

Experience with ospemifene in patients with vulvovaginal atrophy treated with laser therapy: case studies

Drugs in Context, 2020
Vaginal laser therapy is a non-hormonal treatment option for vulvovaginal atrophy (VVA), a component of the genitourinary syndrome of menopause. Through a microablative and/ or thermal effect on atrophic vaginal epithelium, laser therapy activates growth
Félix Lugo Salcedo, Zuramis Estrada Blanco   +1 more
doaj   +1 more source

The REJOICE trial: a phase 3 randomized, controlled trial evaluating the safety and efficacy of a novel vaginal estradiol soft-gel capsule for symptomatic vulvar and vaginal atrophy. [PDF]

, 2017
OBJECTIVE: To evaluate the safety and efficacy of TX-004HR vaginal estradiol soft-gel capsules for moderate-to-severe dyspareunia associated with postmenopausal vulvar and vaginal atrophy.
David F. Archer, Archer, David F, James H. Pickar, Mirkin, Sebastian, Kushner, Harvey, James A. Simon, Gina Gasper, Harvey Kushner, Simon, James A, Bernick, Brian, Brian Bernick, Sebastian Mirkin, Pickar, James H, Graham, Shelli, Ginger D. Constantine, Constantine, Ginger D, Gasper, Gina, Shelli Graham   +17 more
core   +1 more source

Chronic vulvar pain in a cohort of post-menopausal women: Atrophy or Vulvodynia? [PDF]

, 2016
Background Although postmenopausal vulvar pain is frequently attributed to vaginal atrophy, such symptoms may be due to vulvodynia, a chronic vulvar pain condition.
Reed, Barbara D, Siobán D. Harlow, Susanna D. Mitro, Harlow, Siobán D, John F. Randolph, Randolph, John F, Mitro, Susanna D, Barbara D. Reed   +7 more
core   +1 more source

The use of topical vaginal estrogens in postpartum women: A systematic review. [PDF]

Acta Obstet Gynecol Scand
A postpartum reduction in circulating estrogen levels, due to antagonism from elevated prolactin levels, further elevated during breastfeeding, can result in pelvic floor dysfunction, including bladder, bowel and sexual dysfunction, pain and implications for perineal wound healing.
Waheed A, Taithongchai A, Robinson D.
europepmc   +2 more sources

Modulation of vulvovaginal atrophy (VVA) by Gelam honey in bilateral oophorectomized rats

Frontiers in Endocrinology, 2023
IntroductionVulvovaginal atrophy (VVA) is a common condition in post-menopausal women. Symptoms of VVA include dyspareunia, vaginal dryness, vaginal and/or vulvar itching, burning and soreness, dysuria and vaginal bleeding accompanying sexual activity ...
Nur Hilwani Ismail, Nur Hilwani Ismail, Siti Fatimah Ibrahim, Mohd Helmy Mokhtar, Azyani Yahaya, Aini Farzana Zulkefli, Sheril June Ankasha, Khairul Osman   +7 more
doaj   +1 more source

Ospemifene for the treatment of vulvar and vaginal atrophy: A meta-analysis of randomized trials. Part I: Evaluation of efficacy [PDF]

, 2019
Objective: To evaluate the efficacy of ospemifene in treating dyspareunia associated with postmenopausal vulvo-vaginal atrophy (VVA). Methods: A structured search was carried out in PubMed-Medlin, Embase, Cochrane Controlled Trials Register databases ...
Di Donato V., schiavi M. C., D'oria O., Muzii L., iacobelli V., Kontopantelis E., Benedetti Panici P., Simoncini T.   +7 more
core   +2 more sources

VULVAR HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL CHANGES IN PATIENTS WITH PRIMARY SJÖGREN SYNDROME [PDF]

, 2016
Background: Primary Sjogren Syndrome (pSS) is an autoimmune disease mostly affecting women, characterized by a lymphocyte-mediated infiltration and destruction of several exocrine glands, which causes mucosal dryness.
Maddali Bongi S., Orlandi M., Franchi A., De Magnis A.   +3 more
core   +2 more sources

Immune pathogenesis and immune therapy of a sclerosing variant of vulvar lichen sclerosus: a prospective cohort study

Кубанский научный медицинский вестник, 2023
Background. Today, no unified clinical classification of vulvar lichen sclerosus is registered (is yet to be registered?). Isolation of pathogenetically and clinically different variants of its course enable new approaches to the treatment to be ...
E. V. Kolesnikova, A. V. Zharov, M. A. Penzhoyan, D. I. Dupleeva   +3 more
doaj   +1 more source

Structure of Epithelial and Stromal Compartments of Vulvar and Vaginal Tissue From Women With Vulvo-Vaginal Atrophy Taking Ospemifene.

, 2018
INTRODUCTION: Vulvo-vaginal atrophy affects the daily lives of most post-menopausal women. We know that ospemifene intake can induce vaginal epithelial improvements within a few weeks; however, direct evidence of the effects of ospemifene on the human ...
Alvisi S, Meriggiola MC, Seracchioli R, Gava G, Mancini I, Baldassarre M, Gagliardi M   +6 more
core   +1 more source

Effects of Non-Ablative Solid-State Vaginal Laser (SSVL) for the Treatment of Vulvovaginal Atrophy in Breast Cancer Survivors after Adjuvant Aromatase Inhibitor Therapy: Preliminary Results [PDF]

, 2023
Background: One of the side effects of anti-estrogen treatments in breast cancer survivors (BCSs), especially with aromatase inhibitor (AI) treatment, is the frequent appearance of vulvo-vaginal atrophy (VVA).
Butrón-Hinojo, Carmen Aisha, Carmen A. Butrón-Hinojo, Daniel M. Lubián-López, Menjón-Beltrán, S., Silvia Tapiador-Albertos, Tapiador-Albertos, S., Bibiana Rodríguez-Jiménez, Fiol-Ruiz, G., Salomón Menjón-Beltrán, Ernesto González-Mesa, Gabriel Fiol-Ruiz, Lubián López, Daniel María, Rodríguez-Jiménez, B., González-Mesa, Ernesto   +13 more
core   +1 more source