Results 41 to 50 of about 11,148 (154)

Apocrine adenocarcinoma of the vulva

Rare Tumors, 2013
Cutaneous vulvar carcinomas are predominantly of squamous cell carcinoma type. Primary vulvar adenocarcinomas are rare with a poorly understood histogenesis.
Babita Kajal, Hetal Talati, Dean Daya, Salem Alowami   +3 more
doaj   +1 more source

Therapy for Primary Vulvar Carcinoma [PDF]

Geburtshilfe und Frauenheilkunde, 2014
The rather rare vulvar cancer is almost always a squamous cell carcinoma that mostly develops from an underlying VIN or HPV infection. In addition, lichen sclerosus et atrophicans, immune deficiency, nicotine abuse or anogenital intraepithelial neoplasias may play a role in the pathogenesis.
D, Herr, I, Juhasz-Boess, E F, Solomayer
openaire   +2 more sources

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, EarlyView.
What's New? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

Giant vulvar basal cell carcinoma [PDF]

BMJ Case Reports, 2013
We report a case of 30-year-old woman presented with giant, foul smelling ulcerated growth involving the vulva. The growth was involving the whole of labia majora, minora and adjacent skin associated with itching, bleeding and discharge (figure 1). The lesion was atypical in its large size and gross morphology.
Manish, Garg, Pradeep, Sharma, Suhasini, Gupta, Satya Narayan, Sankhwar   +3 more
openaire   +2 more sources

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

One‐year follow‐up after fractionated ultra‐high‐dose‐rate FLASH radiotherapy in patient with extramammary Paget disease of the scrotum

Precision Radiation Oncology, EarlyView.
An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo, Chengliang Yang, Ronghu Mao, Leijie Ma, Hongchang Lei, Peng Chen, Yanping Zhang, Meng Xu, Chao Wang, Yiwu Wang, Mingxia Wu, Chanjun Sun, Han Liu, Hui Liu, Hong Ge   +14 more
wiley   +1 more source

Case report: A kidney metastasis from vulvar squamous cell carcinoma

Frontiers in Oncology
IntroductionDistant metastases of vulvar SCC most commonly involve the lung, liver, bone, skin, and lymph nodes. Metastasis from vulvar SCC to the kidneys is extremely rare, with only one case reported in the literature to date.Case presentationWe report
Junwei He, Junwei He, Yuhe Xiao, Yuhe Xiao, Lu Wang, Lu Wang, Zhaohui Wang, Zhaohui Wang, Jun Pan, Jun Pan, Zunguang Bai, Zunguang Bai   +11 more
doaj   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Treatment of vulvar cancer recurrences with electrochemotherapy – a detailed analysis of possible causes for unsuccessful treatment

Radiology and Oncology, 2023
Electrochemotherapy has good local effectiveness in the treatment of vulvar cancer. Most studies have reported the safety and effectiveness of electrochemotherapy for palliative treatment of gynecological cancers and mostly vulvar squamous cell carcinoma.
Vivod Gregor, Jesenko Tanja, Gasljevic Gorana, Kovacevic Nina, Bosnjak Masa, Sersa Gregor, Merlo Sebastjan, Cemazar Maja   +7 more
doaj   +1 more source

Resecting Beyond the Central Pelvic Compartment in Pelvic Exenterations for Gynaecological Malignancies: Outcomes From a Tertiary Unit

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Pelvic exenterations (PE) in solid organ gynaecological malignancies have historically been confined to the central pelvic compartment but an expansion of resection extent to include the lateral compartment is now technically feasible. There remains uncertainty about its influence on outcomes.
Chia Yew Kong, Norman J. Galbraith, Aiste McCormick, Amy Haddock, Michael Ratcliffe, John Telfer, Steven Lo, Neil Fairbairn, Michael Palmer, Seamus Teahan, Simon Morton, Rhona Lindsay, Kevin Burton, Nadeem Siddiqui, Campbell S. Roxburgh, Peter S. Chong, Colin W. Steele, Martha Quinn   +17 more
wiley   +1 more source