Incidence Trends of Vulvar Cancer in the United States: A 20‐Year Population‐Based Study
Background Despite being uncommon, vulvar cancer is a serious health concern with a 5‐year relative survival rate of 71%. Aims The objective was to investigate the incidence rates of this disease across different racial, ethnic, and histological ...
Seyed Ehsan Mousavi +4 more
doaj +1 more source
Predicting the development of vulvar lichen sclerosus
Relevance. The issue of timely diagnosis and treatment of vulvar lichen sclerosus has become especially acute in recent years due to the “rejuvenation” of the disease and the risk of its malignancy.
Ekaterina V. Kolesnikova +3 more
doaj +1 more source
Economic Burden of Overweight and Obesity in Sweden: Current Estimates and Future Projections
ABSTRACT Aims Overweight and obesity are major public health challenges and well‐established risk factors for cardiovascular disease, cancer and premature mortality. We estimated the economic burden of overweight and obesity in Sweden in 2023 and projected the future economic burden in 2040 under alternative scenarios of increasing prevalence ...
Adam Fridhammar +5 more
wiley +1 more source
Charting the course of Sjögren's disease: A historical analysis of scientific progress
Abstract Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes ...
Diego Ustárroz Cantali +3 more
wiley +1 more source
Hippo pathway disruption and YAP1 activation in anogenital papillary squamous intraepithelial lesion
Disruption of the Hippo Pathway with YAP1 activation is a consistent finding in papillary squamous intraepithelial lesions and may underlie their altered epithelial maturation and HPV E6/E7 expression patterns, providing new insight into the pathogenesis of this distinct low‐risk HPV‐associated lesion.
Gloria Zhang +4 more
wiley +1 more source
Treatment Results of Vulvar Intraepithelial Neoplasia in 16 Women
OBJECTIVE: Clinical outcome after surgical treatment of vulvar intraepithelial neoplasia (VIN). STUDY DESIGN; 16 women with vulvar intraepithelial neoplasia were reviewed.
Cüneyt Eftal Taner +2 more
doaj
Merkel cell carcinoma: an updated guide for pathologists
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley +1 more source
The Potential Coexistence of Autoimmune Thyroid Diseases and Pediatric Vulvar Lichen sclerosus
Introduction: Vulvar lichen sclerosus (VLS), a chronic inflammatory skin disorder, often coexists with autoimmune thyroid disease (AITD). VLS presents with subtle symptoms including vulvar itching and discomfort.
Agnieszka Dulska +3 more
doaj +1 more source
The Impact of Hidradenitis Suppurativa on Sexual Function: A Multicentered Cross‐Sectional Study
Summary of a multicenter study of 522 patients with hidradenitis suppurativa (HS) evaluating quality of life, disease severity, and sexual function. HS was associated with impaired sexual function in both women and men, with pain identified as a central driver.
Defne Özkoca +24 more
wiley +1 more source
Obstetric, somatic and infectious risk factors for vulva sclerotic lichen
Relevance. Until now, disputes among scientists about its etiology, pathogenesis, nomenclature and risk factors for the development of vulvar lichen sclerosis have not subsided, which actualizes the need for scientific research aimed at solving these ...
Lyudmila K. Osipova +3 more
doaj +1 more source

