Results 71 to 80 of about 10,378,896 (295)

JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]

, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana, De Schepper, Sofie, Desmet, Eline, Lambert, Jo, Speeckaert, Reinhart, Van Gele, Mireille   +5 more
core   +2 more sources

HPV‐Related Cancers in Solid Organ Transplant Recipients: A Nationwide Danish Cohort Study

International Journal of Cancer, EarlyView.
Solid organ transplant recipients (SOTRs) face chronic immunosuppression, leaving them susceptible to viral infections. Of particular concern is persistent infection with human papillomavirus (HPV), which presents a significant cancer risk. This nationwide Danish cohort study estimated cancer risk in SOTRs using health registry data.
Signe Timm, Flemming Skjøth, Torben Frøstrup Hansen, Lars Henrik Jensen, Paw Christian Holdgaard, Lars Ulrik Fokdal, Torben Bjerregaard Larsen, Mette Moeller Soerensen   +7 more
wiley   +1 more source

Vulvar and perineal varicose veins in pregnant women

Амбулаторная хирургия, 2019
Pregnancy is an important specific risk factor for the development of chronic vein diseases  in women. In addition  to the superficial veins of the lower limbs, transformation often affects the pelvic veins.
O. V. Dzhenina, V. Yu. Bogachev, А. L. Bodanskaya   +2 more
doaj   +1 more source

PelviSound L—Real‐time intraoperative sonographic assessment of pelvic sentinel lymph nodes using a drop‐in probe in endometrial and cervical cancer during minimally invasive surgery: A single‐center pilot feasibility study in 20 patients

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Sentinel lymph node biopsy (SLNB) is considered an essential step in the surgical management of endometrial and cervical cancers as it has led to a reduction in the need for full pelvic lymphadenectomy. This proof‐of‐concept study aimed to evaluate the feasibility and diagnostic performance of intraoperative sonographic assessment of
Sascha Hoffmann, Laura Trif, Bernhard Krämer, Felix Neis, Diethelm Wallwiener, Sara Y. Brucker, Markus Hoopmann, Markus Hahn   +7 more
wiley   +1 more source

Treatment of symptoms of the menopause: an endocrine society clinical practice guideline [PDF]

, 2015
Objective: The objective of this document is to generate a practice guideline for the management and treatment of symptoms of the menopause. Participants: The Treatment of Symptoms of the Menopause Task Force included six experts, a methodologist, and
Davis, Susan R., Gompel, Anne, Lumsden, Mary Ann, Murad, M. Hassan, Pinkerton, JoAnn V., Santen, Richard J., Stuenkel, Cynthia A.   +6 more
core   +1 more source

Global availability of data on HPV genotype-distribution in cervical, vulvar and vaginal disease and genotype-specific prevalence and incidence of HPV infection in females

Infectious Agents and Cancer, 2015
BackgroundCountry-level HPV genotyping data may be sought by decision-makers to gauge the genotype-specific burden of HPV-related diseases in their jurisdiction and assess the potential impact of HPV vaccines.
M. Wagner, L. Bennetts, Harshila Patel, S. Welner, S. de Sanjosé, T. Weiss   +5 more
semanticscholar   +1 more source

Pelvic venous disorders in women: Diagnosis and management for gynecologists

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pelvic venous disorders (PeVD) are an underrecognized yet significant cause of chronic pelvic pain (CPP) in reproductive‐aged women, characterized by venous reflux, obstruction, or both. This clinical opinion provides a practical overview of PeVD for gynecologists, outlining its pathophysiology, common presentations, diagnostic approach, and ...
Tiffany Ni, Inbar Friedman, Jessica Smith, Brian Liu, Mary Melchior, Andrew D. Brown   +5 more
wiley   +1 more source

Concurrent Occurrence of Rectal Adenocarcinoma and Vulvar Keratinizing Squamous Cell Carcinoma: Case Report and Literature Review

Lietuvos Chirurgija
Introduction. Vulvar carcinoma is a rare malignancy, whereas rectal cancer is a more common oncological condition. However, the simultaneous occurrence of these two diseases is exceptionally rare. Case presentation.
Odeta Laukaitytė, Gustė Brazytė, Tadas Latkauskas, Saulius Paškauskas   +3 more
doaj   +1 more source

Doença de Crohn vulvoperineal responsiva ao metronidazole [PDF]

, 2013
Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological ...
Alves, R., Rosmaninho, A., Salgado, M., Sanches, M., Selores, M.   +4 more
core   +1 more source

Observational study of metastatic vulvar Crohn's disease in the pediatric population

JPGN Reports, EarlyView.
Abstract Objective Metastatic vulvar Crohn's disease (MVCD) is a rare cutaneous manifestation of Crohn's disease (CD), especially in pediatric patients. The objective of this study is to assess presentation, diagnosis, and treatment for pediatric MVCD in the largest cohort reported. Methods This is a retrospective review of pediatric patients with MVCD
Deborah Winograd, Afua Addo, Taryn Wassmer, Jennifer Hellmann, Daniel Mallon, Kalyani Marathe, Christine Pennesi   +6 more
wiley   +1 more source