Results 61 to 70 of about 145,126 (195)

Human papillomavirus infection and p53 protein expression in vulvar intraepithelial neoplasia and invasive squamous cell carcinoma

Brazilian Journal of Medical and Biological Research, 2003
The etiopathogenesis of vulvar intraepithelial neoplasia (VIN III) and invasive squamous cell carcinoma are largely unknown. Since there are few studies on Brazilian patients, our purpose was to determine the frequency of human papillomavirus (HPV ...
D.E.S. Engelman, L.A.L.A. Andrade, J. Vassallo   +2 more
doaj   +1 more source

Two Distinct Pathways to Development of Squamous Cell Carcinoma of the Vulva

Journal of Skin Cancer, 2011
Squamous cell carcinoma (SCC) accounts for approximately 95% of the malignant tumors of the vaginal vulva and is mostly found in elderly women. The future numbers of patients with vulvar SCC is expected to rise, mainly because of the proportional ...
Yutaka Ueda, Takayuki Enomoto, Toshihiro Kimura, Kiyoshi Yoshino, Masami Fujita, Tadashi Kimura   +5 more
doaj   +1 more source

High Prevalence of Human Papillomavirus in Vulvar Cancer Among Vietnamese Women: Implications for Vaccination Strategies

Cancer Medicine, Volume 14, Issue 11, June 2025.
ABSTRACT Background Vulvar cancer (VC) is rare; however, its incidence has steadily increased, likely due to increased human papillomavirus (HPV) infections. HPV infection rates vary significantly with age and ethnicity. Data on the VC incidence in Vietnam are limited. Objectives This study aimed to determine HPV infection rates and high‐risk HPV types
D. N. L. Tran, H. N. Vo, T. T. A. Cung, N. D. Tran, H. N. Cao   +4 more
wiley   +1 more source

Symptom Experience After Surgical Treatment for Vulvar Cancer—A Scoping Review

Scandinavian Journal of Caring Sciences, Volume 39, Issue 2, June 2025.
ABSTRACT Background Previous reviews have indicated a high burden of physical, emotional and sexual symptoms in women who have undergone surgery for vulvar cancer. Numerous surgical modifications have been made over the past few decades to limit post‐operative symptoms.
Anne Marie Thimm, Eva Helena Hansson, Katrine Bak Wraae, Mette Linnet Olesen   +3 more
wiley   +1 more source

Clinical validation of methylation biomarkers for optimal detection of high-grade vulvar intraepithelial neoplasia

, 2023
The precursor lesions of vulvar squamous cell carcinoma (VSCC) include human papillomavirus (HPV)-associated and HPV-independent squamous neoplasia with a varying cancer risk.
Voss, F. line O., Steenbergen, Renske D. M., Thuijs, Nikki B., Duin, Sylvia, Özer, M. jde, Berkhof, Johannes, Bleeker, Maaike C. G., van Beurden, Marc   +7 more
core   +1 more source

Diagnosis of Vulvar Lesions by Non-Invasive Optical Analysis: A Pilot Study

Rare Tumors, 2009
A procedure that could allow an early in vivo and non-invasive detection of vulvar lesions would be extremely useful. We tested an innovative optical method (Optiprobe), which uses a harmless, visible light source for the in vivo , on-line detection of ...
Anne-Therese Vlastos, Igor Charvet, Ilaria Dellacasa, Federica Capanna, Marie-Françoise Pelte, Philippe Thueler, Michel Saint-Ghislain, Christian Depeursinge, Paolo Meda   +8 more
doaj   +1 more source

Human papillomavirus detection in genital lesions by in situ hybridization and ultrastructural observations

Memorias do Instituto Oswaldo Cruz, 1994
Detection of papillomavirus DNA in sity hybridization technique was perfomed in 29 symptomatic patients (6 males and 23 females) during the period of 1989-1991 at the Clinic for Sexually Transmitted Diseases, Universidade Federal Fluminense, State of rio
L. H. S. Oliveira, I. C. P. P. Frugulhetti, M. R. L. Passos, S. M. B. Cavalcanti, M. E. F. Fonseca   +4 more
doaj   +1 more source

Antiviral activity of curcumin-nanoemulsion associated with photodynamic therapy in vulvar cell lines transducing different variants of HPV-16

Artificial Cells, Nanomedicine, and Biotechnology, 2020
Vulvar intraepithelial neoplasia (VIN) is associated with human papillomavirus (HPV) infection. Curcumin is a natural bioactive compound with antineoplastic properties. The use of nanoparticles containing curcumin could allow a better performance of this
Caroline Measso do Bonfim, Letícia Figueiredo Monteleoni, Marília de Freitas Calmon, Natália Maria Cândido, Paola Jocelan Scarin Provazzi, Vanesca de Souza Lino, Tatiana Rabachini, Laura Sichero, Luisa Lina Villa, Silvana Maria Quintana, Patrícia Pereira dos Santos Melli, Fernando Lucas Primo, Camila Fernanda Amantino, Antonio Claudio Tedesco, Enrique Boccardo, Paula Rahal   +15 more
doaj   +1 more source

DNA methylation and copy number alterations in the progression of HPV‐associated high‐grade vulvar intraepithelial lesion

International Journal of Cancer, Volume 156, Issue 10, Page 1926-1935, 15 May 2025.
What's new? Patients with human papillomavirus (HPV)‐associated high‐grade vulvar intraepithelial lesion (HSIL) often undergo damaging treatments to prevent progression to cancer. Molecular characterization of HSIL to assess progression risk could reduce the need for aggressive interventions. Here, cancer risk stratification of HSIL was investigated by
Flavia Runello, Aude Jary, Sylvia Duin, Yongsoo Kim, Kahren van Eer, Féline O. Voss, Nikki B. Thuijs, Maaike C. G. Bleeker, Renske D. M. Steenbergen   +8 more
wiley   +1 more source

Presence of human papilloma virus in Caucasian women living in the central Europe diagnosed with vulvar intraepithelial neoplasia [PDF]

, 2020
Objectives: The role of human papilloma virus (HPV) in the development of cancerous states of female reproductive tracthas been widely debated. However, the information about presence of HPV in the Caucasian women living in the centralEurope diagnosed ...
Gabriel, Iwona; Medical University of Silesia, Katowice, Poland, Olejek, Anita; Medical University of Silesia, Katowice, Poland, Drozdzowska, Bogna; Medical University of Silesia, Katowice, Poland, Witek, Lukasz; Medical University of Silesia, Katowice, Poland, Robenek, Marta; Medical University of Silesia, Katowice, Poland, Augusciak-Duma, Aleksandra; Medical University of Silesia, Katowice, Poland   +5 more
core   +1 more source