Results 1 to 10 of about 8,399 (207)

Successful Microablative Fractional Carbon Dioxide Laser Therapy for Vulvar Lichen Sclerosus: A Case Report and Mini-review [PDF]

Gynecology and Minimally Invasive Therapy
Vulvar lichen sclerosus (VLS) is a chronic inflammatory skin disorder affecting the vulvar region. VLS predominantly affects women, and most cases occur after menopause.
Wen-Lin Hsieh, Dah-Ching Ding
doaj   +3 more sources

Vulvar lichen sclerosus et atrophicus: Refractory to standard therapy

Journal of Indian Association of Pediatric Surgeons, 2023
Vulvar lichen sclerosus et atrophicus is an inflammatory disease which can affect the pediatric age group, although rarely. Its prevalence is underestimated. It may have genital or extragenital manifestations.
Thasneem S Luqman, Akshay Kalavant, K S Sunil Kumar, A R Swathy   +3 more
doaj   +4 more sources

Vulvar lichen sclerosus. [PDF]

CMAJ, 2021
An otherwise healthy 71-year-old woman presented to our clinic with a history of pruritus and burning of the vulva. On examination, we observed an atrophic, white, shiny plaque involving the vulva, perineum and perianal areas.
Cleminson K, Baxter ML.
europepmc   +4 more sources

Regenerative Approaches in Vulvar Lichen Sclerosus: A Systematic Review. [PDF]

Int J Mol Sci
Vulvar lichen sclerosus (VLS) involves chronic inflammation, immune dysregulation, and abnormal extracellular matrix remodeling, involving extracellular matrix protein 1 (ECM1) and non-coding RNAs, particularly miR-155.
Beutler K, Jankowska-Konsur A, Nowicka D.   +2 more
europepmc   +2 more sources

Trends and Developments in Vulvar Lichen Sclerosus Research. [PDF]

Health Sci Rep
Despite the prevalence of vulvar lichen sclerosus (VLS) as a chronic skin disease in clinical settings, there is a notable absence of a comprehensive bibliometric analysis summarizing the existing literature on this topic.
He FR, Lin YR, Wen YH, Deng JH.
europepmc   +2 more sources

Cutaneous dysbiosis in girls with vulvar lichen sclerosus. [PDF]

Microbiol Spectr
Vulvar lichen sclerosus (VLS) is a chronic skin condition affecting the vulva, causing significant discomfort, but its etiology in prepubertal girls remains poorly understood. VLS presents with itching, irritation, and pain.
Sun L, Gao H, Chen H, Ren C, Zhang J, Shen Q, Zhu L, Chen D, Jin L, Wang C, Li F, Yu L.   +11 more
europepmc   +2 more sources

A Guide to Screening for Autoimmune Diseases in Patients With Vulvar Lichen Sclerosus. [PDF]

Australas J Dermatol
The aetiology of vulvar lichen sclerosus (VLS) remains unknown. However, there is evidence that in addition to a genetic predisposition, autoimmunity contributes to the pathogenesis.
Guttentag A, Wijaya M, Fischer GO, Lee A, Liu K, Saunderson RB.   +5 more
europepmc   +2 more sources

Paediatric and adolescent vulvar lichen sclerosus: delay in diagnosis. [PDF]

Eur J Pediatr
Vulvar Lichen Sclerosus(VLS) is an uncommon, often misdiagnosed condition with a chronic course. Children presenting with VLS may have a wide variety of complaints, which complicates diagnosis.
Crofts VL, Moussaoui D, Shynkarova V, Yaron M.   +3 more
europepmc   +2 more sources

Spatial and Single-Cell Transcriptomics Reveal Keratinocytes as Key Players in Vulvar Lichen Sclerosus Pathogenesis. [PDF]

J Invest Dermatol
Vulvar diseases are a neglected area of women's health, profoundly affecting patients' quality of life. Lichen sclerosus (LS) is a chronic inflammatory vulvar skin disorder leading to severe itching, pain, scarring, and an increased risk of malignancy ...
Sun P, Kraus CN, Zhao W, Xu J, Suh S, Nguyen Q, Jia Y, Nair A, Oakes M, Tinoco R, Shiu J, Sun B, Elsensohn A, Atwood SX, Nie Q, Dai X.   +15 more
europepmc   +2 more sources

VALOR DE LA BIOPSIA VULVAR EN EL DIAGNÓSTICO DE LIQUEN ESCLEROSO EN PACIENTES CON ALTERACIONES VULVARES CRÓNICAS [PDF]

Revista Chilena de Obstetricia y Ginecología, 2004
Se presenta un estudio prospectivo donde se realizó biopsia vulvar a pacientes con síntomas y/o alteraciones vulvares crónicas de más de un año de evolución.
Pablo Sanhueza R, Nicole Yaksic B, Karina Chahuán I   +2 more
doaj   +4 more sources