Results 191 to 200 of about 3,759 (215)
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Experimental Dermatology, 2022
AbstractVulvar lichen sclerosus (VLS) confers approximately 3% risk of malignant transformation to vulvar squamous cell carcinoma (VSCC). We used unbiased proteomic methods to identify differentially expressed proteins in tissue of patients with VLS who developed VSCC compared to those who did not.
Casey A. Gleue +9 more
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AbstractVulvar lichen sclerosus (VLS) confers approximately 3% risk of malignant transformation to vulvar squamous cell carcinoma (VSCC). We used unbiased proteomic methods to identify differentially expressed proteins in tissue of patients with VLS who developed VSCC compared to those who did not.
Casey A. Gleue +9 more
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Risk factors for vulvar lichen sclerosus
American Journal of Obstetrics and Gynecology, 1989To assess risk factors for vulvar lichen sclerosus data were collected in a case-control study of 75 cases and 225 age-matched control subjects. Questions concerned personal characteristics and habits, gynecologic and obstetric data, general indicators of sexual habits, and selected dietary habits.
M. Sideri +7 more
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Comorbid Vulvar Lichen Planus and Lichen Sclerosus
Journal of Lower Genital Tract Disease, 2017Objectives The aims of the study are to assess the histopathologic characteristics of vulvar biopsies consistent with lichen planus (LP) in women with a previous or concurrent histopathologic diagnosis of vulvar lichen sclerosus (LS) and to describe the clinical features of comorbid LP and LS ...
Day, Tania +3 more
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Genetic aspects of vulvar lichen sclerosus
American Journal of Obstetrics and Gynecology, 1984Thirteen instances of familial lichen sclerosus have been recorded in the literature. This report documents the disease in two additional families and adds genetic data on their HLA characteristics. The relationship of these factors to a possible autoimmune mechanism for the disease is discussed.
E G, Friedrich, N K, MacLaren
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Annales de dermatologie et de venereologie, 2005
Vulvar lichen sclerosus is a frequent mucocutaneous disease especially affecting 50 to 60 year-old women but with a possible onset at very young age. Symptoms are most disabling including pruritus and dyspareunia. Vulvar mucosa gradually becomes more white and atrophied. Degeneration into epidermoid carcinoma is possible.
L, Labbé, C, Léauté-Labrèze
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Vulvar lichen sclerosus is a frequent mucocutaneous disease especially affecting 50 to 60 year-old women but with a possible onset at very young age. Symptoms are most disabling including pruritus and dyspareunia. Vulvar mucosa gradually becomes more white and atrophied. Degeneration into epidermoid carcinoma is possible.
L, Labbé, C, Léauté-Labrèze
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Coexistence of oral lichen planus and vulvar lichen sclerosus
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2023Oral lichen planus (OLP) is a mucosal variant of lichen planus. Lichen sclerosus (LS) is an inflammatory disorder with a predilection for genital skin. We aimed to identify the characteristics of patients with both mucosal diagnoses.This retrospective study included 86 women with both OLP and vulvar LS diagnosed from June 1, 1991 through November 30 ...
Marketa, Janovska +3 more
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Calcineurin antagonists in vulvar lichen sclerosus
Archives of Gynecology and Obstetrics, 2006Lichen sclerosus et atrophicus is a chronic inflammatory disorder that mainly affects girls of premenarchial age and women in their fifties. Besides the anogenital region, lichen sclerosus (LS) may also affect extragenital or mucosal areas. Symptoms include soreness and pruritus, but other less common symptoms are not rare.
Hans J, Strittmatter +2 more
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Early vulvar lichen sclerosus: a histopathological challenge
Histopathology, 2005Vulvar lichen sclerosus (LS), a lymphocyte‐mediated chronic skin disease, begins with uncharacteristic symptoms and progresses undiagnosed to atrophy and destructive scarring. Some patients with longstanding advanced LS have an increased risk of vulvar carcinoma. Early LS is treatable, although not curable, if diagnosed early.
S, Regauer, B, Liegl, O, Reich
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Vulvar squamous cell carcinoma and lichen sclerosus
Australasian Journal of Dermatology, 1997There are two clinicopathological types of vulvar squamous cell carcinoma, human papillomavirus (HPV)-positive and HPV-negative, which can be distinguished to some degree on routine histology. Human papillomavirus-positive carcinomas account for one-quarter to one-third of cases, occur in women on average 20 years younger than in HPV-negative, and are ...
J P, Scurry, K, Vanin
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Topical tacrolimus for recalcitrant vulvar lichen sclerosus
European Journal of Dermatology, 2009Auteur(s) : Eleni Sotiriou, Zoi Apalla, Aikaterini Patsatsi, Despina Panagiotidou First dermatologic department, Medical school, Aristotle university Thessaloniki, 8, Papakyriazi str, 54645 Thessaloniki, Greece Vulvar lichen sclerosus (VLS) is a chronic inflammatory skin disorder of uncertain origin predominantly affecting postmenopausal women.
Eleni, SOTIRIOU +3 more
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